State Cancer Profiles

Interpretation of Historical Trends Data

Historical Trends (1990-2022)

Mortality, North Carolina, All Cancer Sites, All Races (incl Hisp), All Ages, Male

Mortality, North Carolina, All Cancer Sites, All Races (incl Hisp), All Ages, Male

Line graph with 33 years and 2 segments
During 1990-1996, the APC¹ in the rate of cancer was stable: -0.5 with a 95% confidence interval from -1.1 to 0.6.
During 1996-2022, the APC¹ in the rate of cancer was falling: -1.8 with a 95% confidence interval from -1.9 to -1.7.
Yearly points:
In 1990, the observed rate was 297.6. The estimated rate was 297.8.
In 1991, the observed rate was 292.7. The estimated rate was 296.2.
In 1992, the observed rate was 294.5. The estimated rate was 294.6.
In 1993, the observed rate was 299.0. The estimated rate was 293.1.
In 1994, the observed rate was 292.4. The estimated rate was 291.5.
In 1995, the observed rate was 288.2. The estimated rate was 289.9.
In 1996, the observed rate was 287.5. The estimated rate was 288.4.
In 1997, the observed rate was 277.7. The estimated rate was 283.2.
In 1998, the observed rate was 277.3. The estimated rate was 278.1.
In 1999, the observed rate was 274.7. The estimated rate was 273.2.
In 2000, the observed rate was 271.4. The estimated rate was 268.3.
In 2001, the observed rate was 264.6. The estimated rate was 263.5.
In 2002, the observed rate was 259.9. The estimated rate was 258.8.
In 2003, the observed rate was 250.1. The estimated rate was 254.2.
In 2004, the observed rate was 248.7. The estimated rate was 249.6.
In 2005, the observed rate was 244.3. The estimated rate was 245.2.
In 2006, the observed rate was 243.9. The estimated rate was 240.8.
In 2007, the observed rate was 238.1. The estimated rate was 236.5.
In 2008, the observed rate was 229.4. The estimated rate was 232.3.
In 2009, the observed rate was 225.4. The estimated rate was 228.1.
In 2010, the observed rate was 225.8. The estimated rate was 224.0.
In 2011, the observed rate was 222.1. The estimated rate was 220.0.
In 2012, the observed rate was 212.6. The estimated rate was 216.1.
In 2013, the observed rate was 213.0. The estimated rate was 212.2.
In 2014, the observed rate was 213.9. The estimated rate was 208.5.
In 2015, the observed rate was 208.1. The estimated rate was 204.7.
In 2016, the observed rate was 202.3. The estimated rate was 201.1.
In 2017, the observed rate was 195.0. The estimated rate was 197.5.
In 2018, the observed rate was 193.7. The estimated rate was 194.0.
In 2019, the observed rate was 191.7. The estimated rate was 190.5.
In 2020, the observed rate was 185.6. The estimated rate was 187.1.
In 2021, the observed rate was 179.8. The estimated rate was 183.7.
In 2022, the observed rate was 181.2. The estimated rate was 180.5.

Notes:

• Created by statecancerprofiles.cancer.gov on 07/18/2025 6:44 pm.
• Regression lines calculated using the Joinpoint Regression Program (Version 5.3.0).
• ¹ The APC is the Annual Percent Change over the time interval. Rates used in the calculation of the APC are age-adjusted to the 2000 US standard population (19 age groups: <1, 1-4, 5-9, ... , 80-84, 85+).


• Explanation of the Calculation of the Trend:
  If the APC is less than -1.5, the trend is falling.
  If the APC is between -1.5 and -0.5, the trend is slightly falling.
  If the APC is between -0.5 and 0.5, the trend is statistically stable.
  If the APC is between 0.5 and 1.5, the trend is slightly rising.
  If the APC is greater than 1.5, the trend is rising.

  
  Source: Incidence data provided by the SEER Program and the National Program of Cancer Registries SEER*Stat Database United States Department of Health and Human Services, Centers for Disease Control and Prevention. Rates calculated by the National Cancer Institute using SEER*Stat. Rates are age-adjusted to the 2000 US standard population (19 age groups: <1, 1-4, 5-9, ... , 80-84, 85+). Rates are for invasive cancer only (except for bladder cancer which is invasive and in situ) or unless otherwise specified. Population counts for denominators are based on Census populations as modified by NCI. The US populations included with the data release have been adjusted for the population shifts due to hurricanes Katrina and Rita for 62 counties and parishes in Alabama, Mississippi, Louisiana, and Texas. The US Population Data File is used with SEER data. Rates and trends in this graph are computed using the same standard for malignancy. For more information see malignant.html
  
  Source: Death data provided by the National Vital Statistics System public use data file. Death rates calculated by the National Cancer Institute using SEER*Stat. Death rates (deaths per 100,000 population per year) are age-adjusted to the 2000 US standard population (19 age groups: (<1, 1-4, 5-9, ... , 80-84, 85+). Population counts for denominators are based on Census populations as modified by NCI. The US populations included with the data release have been adjusted for the population shifts due to hurricanes Katrina and Rita for 62 counties and parishes in Alabama, Mississippi, Louisiana, and Texas. US Population Data File is used with mortality data.