State Cancer Profiles

Interpretation of Historical Trends Data

Historical Trends (1990-2022)

Mortality, North Carolina, All Cancer Sites, All Races (incl Hisp), All Ages, Female

Mortality, North Carolina, All Cancer Sites, All Races (incl Hisp), All Ages, Female

Line graph with 33 years and 2 segments
During 1990-2001, the APC¹ in the rate of cancer was stable: -0.2 with a 95% confidence interval from -0.4 to 0.3.
During 2001-2022, the APC¹ in the rate of cancer was falling: -1.2 with a 95% confidence interval from -1.3 to -1.1.
Yearly points:
In 1990, the observed rate was 165.2. The estimated rate was 166.6.
In 1991, the observed rate was 163.4. The estimated rate was 166.3.
In 1992, the observed rate was 167.7. The estimated rate was 166.0.
In 1993, the observed rate was 167.3. The estimated rate was 165.8.
In 1994, the observed rate was 166.5. The estimated rate was 165.5.
In 1995, the observed rate was 167.0. The estimated rate was 165.2.
In 1996, the observed rate was 166.3. The estimated rate was 165.0.
In 1997, the observed rate was 163.8. The estimated rate was 164.7.
In 1998, the observed rate was 161.5. The estimated rate was 164.4.
In 1999, the observed rate was 165.8. The estimated rate was 164.2.
In 2000, the observed rate was 161.5. The estimated rate was 163.9.
In 2001, the observed rate was 164.5. The estimated rate was 163.6.
In 2002, the observed rate was 162.8. The estimated rate was 161.8.
In 2003, the observed rate was 159.0. The estimated rate was 159.9.
In 2004, the observed rate was 158.7. The estimated rate was 158.1.
In 2005, the observed rate was 157.4. The estimated rate was 156.2.
In 2006, the observed rate was 157.2. The estimated rate was 154.4.
In 2007, the observed rate was 154.3. The estimated rate was 152.7.
In 2008, the observed rate was 149.1. The estimated rate was 150.9.
In 2009, the observed rate was 144.7. The estimated rate was 149.2.
In 2010, the observed rate was 145.4. The estimated rate was 147.4.
In 2011, the observed rate was 143.9. The estimated rate was 145.7.
In 2012, the observed rate was 144.0. The estimated rate was 144.1.
In 2013, the observed rate was 140.7. The estimated rate was 142.4.
In 2014, the observed rate was 142.9. The estimated rate was 140.7.
In 2015, the observed rate was 140.1. The estimated rate was 139.1.
In 2016, the observed rate was 139.9. The estimated rate was 137.5.
In 2017, the observed rate was 138.4. The estimated rate was 135.9.
In 2018, the observed rate was 134.1. The estimated rate was 134.4.
In 2019, the observed rate was 132.6. The estimated rate was 132.8.
In 2020, the observed rate was 130.5. The estimated rate was 131.3.
In 2021, the observed rate was 131.8. The estimated rate was 129.8.
In 2022, the observed rate was 125.5. The estimated rate was 128.3.

Notes:

• Created by statecancerprofiles.cancer.gov on 05/13/2025 3:15 am.
• Regression lines calculated using the Joinpoint Regression Program (Version 5.3.0).
• ¹ The APC is the Annual Percent Change over the time interval. Rates used in the calculation of the APC are age-adjusted to the 2000 US standard population (19 age groups: <1, 1-4, 5-9, ... , 80-84, 85+).


• Explanation of the Calculation of the Trend:
  If the APC is less than -1.5, the trend is falling.
  If the APC is between -1.5 and -0.5, the trend is slightly falling.
  If the APC is between -0.5 and 0.5, the trend is statistically stable.
  If the APC is between 0.5 and 1.5, the trend is slightly rising.
  If the APC is greater than 1.5, the trend is rising.

  
  Source: Incidence data provided by the SEER Program and the National Program of Cancer Registries SEER*Stat Database United States Department of Health and Human Services, Centers for Disease Control and Prevention. Rates calculated by the National Cancer Institute using SEER*Stat. Rates are age-adjusted to the 2000 US standard population (19 age groups: <1, 1-4, 5-9, ... , 80-84, 85+). Rates are for invasive cancer only (except for bladder cancer which is invasive and in situ) or unless otherwise specified. Population counts for denominators are based on Census populations as modified by NCI. The US populations included with the data release have been adjusted for the population shifts due to hurricanes Katrina and Rita for 62 counties and parishes in Alabama, Mississippi, Louisiana, and Texas. The US Population Data File is used with SEER data. Rates and trends in this graph are computed using the same standard for malignancy. For more information see malignant.html
  
  Source: Death data provided by the National Vital Statistics System public use data file. Death rates calculated by the National Cancer Institute using SEER*Stat. Death rates (deaths per 100,000 population per year) are age-adjusted to the 2000 US standard population (19 age groups: (<1, 1-4, 5-9, ... , 80-84, 85+). Population counts for denominators are based on Census populations as modified by NCI. The US populations included with the data release have been adjusted for the population shifts due to hurricanes Katrina and Rita for 62 counties and parishes in Alabama, Mississippi, Louisiana, and Texas. US Population Data File is used with mortality data.