Interpretation of Incidence Rates Data
Incidence Rate Report for South Carolina by County
All Cancer Sites (All Stages^), 2018-2022
All Races (includes Hispanic), Female, All Ages
Sorted by CI*Rank
Explanation of Column HeadersIncidence Rate (95% Confidence Interval) - The incidence rate is based upon 100,000 people and is an annual rate (or average annual rate) based on the time period indicated. Rates are age-adjusted by 5-year age groups to the 2000 U.S. standard million population.
Recent Trends - This is an interpretation of the AAPC/APC:
- Rising when 95% confidence interval of AAPC/APC is above 0.
- Stable when 95% confidence interval of AAPC/APC includes 0.
- Falling when 95% confidence interval of AAPC/APC is below 0.
AAPC/APC (95% Confidence Interval) - the change in rate over time
- Average Annual Percent Change - AAPCs are based upon APCs that were calculated by Joinpoint Regression Program
- Annual Percent Change - APCs calculated in SEER*Stat.
Other Notes
- Larger confidence intervals indicate less stability of the data. This is often due to low counts that are not quite low enough to be suppressed.
- Data is currently being suppressed if there are fewer than 16 counts for the time period.
Line by Line Interpretation of the Report
South Carolina2
- 2023 Rural-Urban Continuum Codes Φ : N/A
- Rate : The incidence rate is 409.9 with a 95% confidence interval from 406.8 to 413.1 and 14,288 average annual cases over 2018-2022.
- CI*Rank ⋔ : N/A
- Recent Trend : The trend is because the trend is -0.7 with a 95% confidence interval from -1.2 to -0.3.
US (SEER+NPCR)1
- 2023 Rural-Urban Continuum Codes Φ : N/A
- Rate : The incidence rate is 424.8 with a 95% confidence interval from 424.4 to 425.2 and 891,437 average annual cases over 2018-2022.
- CI*Rank ⋔ : N/A
- Recent Trend : The trend is because the trend is -0.6 with a 95% confidence interval from -1.1 to -0.1.
Greenwood County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 459.9 with a 95% confidence interval from 431.9 to 489.4 and 222 average annual cases over 2018-2022.
- CI*Rank ⋔ : 1 (1, 20)
- Recent Trend : The trend is because the trend is 3.7 with a 95% confidence interval from 0.8 to 8.3.
Hampton County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 459.1 with a 95% confidence interval from 404.1 to 520.1 and 57 average annual cases over 2018-2022.
- CI*Rank ⋔ : 2 (1, 34)
- Recent Trend : The trend is because the trend is 5.3 with a 95% confidence interval from 2.6 to 10.8.
Colleton County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 451.5 with a 95% confidence interval from 415.0 to 490.7 and 126 average annual cases over 2018-2022.
- CI*Rank ⋔ : 3 (1, 29)
- Recent Trend : The trend is because the trend is 0.5 with a 95% confidence interval from -0.6 to 1.5.
Orangeburg County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 440.9 with a 95% confidence interval from 416.4 to 466.6 and 277 average annual cases over 2018-2022.
- CI*Rank ⋔ : 4 (1, 26)
- Recent Trend : The trend is because the trend is 0.9 with a 95% confidence interval from 0.3 to 1.4.
Greenville County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 440.8 with a 95% confidence interval from 430.5 to 451.3 and 1,476 average annual cases over 2018-2022.
- CI*Rank ⋔ : 5 (2, 17)
- Recent Trend : The trend is because the trend is 0.5 with a 95% confidence interval from 0.2 to 0.8.
Dorchester County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 440.1 with a 95% confidence interval from 421.1 to 459.7 and 425 average annual cases over 2018-2022.
- CI*Rank ⋔ : 6 (1, 23)
- Recent Trend : The trend is because the trend is 0.3 with a 95% confidence interval from -0.3 to 1.0.
Cherokee County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 438.1 with a 95% confidence interval from 407.5 to 470.6 and 162 average annual cases over 2018-2022.
- CI*Rank ⋔ : 7 (1, 31)
- Recent Trend : The trend is because the trend is 0.4 with a 95% confidence interval from -0.3 to 1.1.
Union County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 436.5 with a 95% confidence interval from 394.4 to 482.2 and 91 average annual cases over 2018-2022.
- CI*Rank ⋔ : 8 (1, 35)
- Recent Trend : The trend is because the trend is 0.8 with a 95% confidence interval from -0.1 to 1.8.
Georgetown County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 435.0 with a 95% confidence interval from 407.3 to 464.3 and 248 average annual cases over 2018-2022.
- CI*Rank ⋔ : 9 (1, 30)
- Recent Trend : The trend is because the trend is -3.9 with a 95% confidence interval from -8.1 to 0.5.
Oconee County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 433.2 with a 95% confidence interval from 408.1 to 459.5 and 266 average annual cases over 2018-2022.
- CI*Rank ⋔ : 10 (1, 30)
- Recent Trend : The trend is because the trend is 0.1 with a 95% confidence interval from -0.4 to 0.7.
Dillon County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 431.0 with a 95% confidence interval from 388.9 to 476.7 and 84 average annual cases over 2018-2022.
- CI*Rank ⋔ : 11 (1, 36)
- Recent Trend : The trend is because the trend is 0.4 with a 95% confidence interval from -1.2 to 2.0.
Lexington County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 429.8 with a 95% confidence interval from 416.4 to 443.6 and 819 average annual cases over 2018-2022.
- CI*Rank ⋔ : 12 (3, 23)
- Recent Trend : The trend is because the trend is 0.3 with a 95% confidence interval from 0.0 to 0.7.
Spartanburg County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 428.4 with a 95% confidence interval from 415.7 to 441.6 and 901 average annual cases over 2018-2022.
- CI*Rank ⋔ : 13 (4, 24)
- Recent Trend : The trend is because the trend is 0.2 with a 95% confidence interval from -0.2 to 0.5.
Pickens County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 427.9 with a 95% confidence interval from 406.8 to 449.8 and 342 average annual cases over 2018-2022.
- CI*Rank ⋔ : 14 (2, 30)
- Recent Trend : The trend is because the trend is -2.8 with a 95% confidence interval from -5.7 to 0.4.
Charleston County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 426.6 with a 95% confidence interval from 415.1 to 438.3 and 1,137 average annual cases over 2018-2022.
- CI*Rank ⋔ : 15 (5, 24)
- Recent Trend : The trend is because the trend is -0.1 with a 95% confidence interval from -0.4 to 0.2.
Chester County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 423.3 with a 95% confidence interval from 384.5 to 465.4 and 96 average annual cases over 2018-2022.
- CI*Rank ⋔ : 16 (1, 38)
- Recent Trend : The trend is because the trend is 0.7 with a 95% confidence interval from -0.4 to 1.8.
Kershaw County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 419.9 with a 95% confidence interval from 392.5 to 448.8 and 193 average annual cases over 2018-2022.
- CI*Rank ⋔ : 17 (2, 34)
- Recent Trend : The trend is because the trend is -0.3 with a 95% confidence interval from -0.9 to 0.3.
Marion County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 418.4 with a 95% confidence interval from 379.4 to 460.8 and 95 average annual cases over 2018-2022.
- CI*Rank ⋔ : 18 (1, 38)
- Recent Trend : The trend is because the trend is 1.1 with a 95% confidence interval from 0.1 to 2.1.
Marlboro County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 417.5 with a 95% confidence interval from 374.5 to 464.5 and 77 average annual cases over 2018-2022.
- CI*Rank ⋔ : 19 (1, 40)
- Recent Trend : The trend is because the trend is 0.3 with a 95% confidence interval from -0.5 to 1.1.
Horry County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 413.4 with a 95% confidence interval from 401.8 to 425.2 and 1,197 average annual cases over 2018-2022.
- CI*Rank ⋔ : 20 (10, 31)
- Recent Trend : The trend is because the trend is -0.8 with a 95% confidence interval from -4.3 to 0.2.
Clarendon County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 412.1 with a 95% confidence interval from 374.1 to 453.4 and 106 average annual cases over 2018-2022.
- CI*Rank ⋔ : 21 (1, 39)
- Recent Trend : The trend is because the trend is 0.6 with a 95% confidence interval from -0.9 to 2.2.
McCormick County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 410.9 with a 95% confidence interval from 340.4 to 496.3 and 41 average annual cases over 2018-2022.
- CI*Rank ⋔ : 22 (1, 46)
- Recent Trend : The trend is because the trend is -0.1 with a 95% confidence interval from -1.8 to 1.5.
Anderson County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 407.2 with a 95% confidence interval from 391.7 to 423.2 and 567 average annual cases over 2018-2022.
- CI*Rank ⋔ : 23 (11, 33)
- Recent Trend : The trend is because the trend is -0.2 with a 95% confidence interval from -0.5 to 0.2.
York County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 405.9 with a 95% confidence interval from 392.2 to 419.9 and 697 average annual cases over 2018-2022.
- CI*Rank ⋔ : 24 (13, 33)
- Recent Trend : The trend is because the trend is -3.5 with a 95% confidence interval from -7.9 to -0.5.
Laurens County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 405.5 with a 95% confidence interval from 379.1 to 433.5 and 193 average annual cases over 2018-2022.
- CI*Rank ⋔ : 25 (4, 38)
- Recent Trend : The trend is because the trend is -4.3 with a 95% confidence interval from -7.9 to 0.0.
Florence County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 404.4 with a 95% confidence interval from 385.8 to 423.7 and 382 average annual cases over 2018-2022.
- CI*Rank ⋔ : 26 (9, 35)
- Recent Trend : The trend is because the trend is 0.3 with a 95% confidence interval from -0.3 to 1.0.
Berkeley County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 404.2 with a 95% confidence interval from 388.5 to 420.3 and 537 average annual cases over 2018-2022.
- CI*Rank ⋔ : 27 (12, 34)
- Recent Trend : The trend is because the trend is 0.0 with a 95% confidence interval from -0.7 to 0.8.
Newberry County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 404.0 with a 95% confidence interval from 368.8 to 442.0 and 109 average annual cases over 2018-2022.
- CI*Rank ⋔ : 28 (2, 41)
- Recent Trend : The trend is because the trend is 0.2 with a 95% confidence interval from -0.9 to 1.2.
Darlington County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 399.8 with a 95% confidence interval from 373.0 to 428.2 and 182 average annual cases over 2018-2022.
- CI*Rank ⋔ : 29 (6, 39)
- Recent Trend : The trend is because the trend is 0.5 with a 95% confidence interval from -0.3 to 1.2.
Sumter County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 392.3 with a 95% confidence interval from 370.7 to 414.8 and 271 average annual cases over 2018-2022.
- CI*Rank ⋔ : 30 (14, 39)
- Recent Trend : The trend is because the trend is 0.0 with a 95% confidence interval from -0.9 to 1.0.
Abbeville County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 386.9 with a 95% confidence interval from 344.6 to 433.5 and 72 average annual cases over 2018-2022.
- CI*Rank ⋔ : 31 (3, 45)
- Recent Trend : The trend is because the trend is 1.0 with a 95% confidence interval from -0.2 to 2.2.
Chesterfield County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 384.7 with a 95% confidence interval from 352.5 to 419.2 and 117 average annual cases over 2018-2022.
- CI*Rank ⋔ : 32 (9, 43)
- Recent Trend : The trend is because the trend is -4.3 with a 95% confidence interval from -9.9 to 0.0.
Bamberg County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 381.1 with a 95% confidence interval from 326.4 to 443.4 and 42 average annual cases over 2018-2022.
- CI*Rank ⋔ : 33 (1, 46)
- Recent Trend : The trend is because the trend is -3.6 with a 95% confidence interval from -14.3 to 0.9.
Richland County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 379.5 with a 95% confidence interval from 368.2 to 391.1 and 902 average annual cases over 2018-2022.
- CI*Rank ⋔ : 34 (26, 39)
- Recent Trend : The trend is because the trend is -3.1 with a 95% confidence interval from -6.0 to -1.1.
Beaufort County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 371.8 with a 95% confidence interval from 356.8 to 387.4 and 596 average annual cases over 2018-2022.
- CI*Rank ⋔ : 35 (27, 42)
- Recent Trend : The trend is because the trend is -2.0 with a 95% confidence interval from -5.2 to -0.8.
Fairfield County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 369.5 with a 95% confidence interval from 325.6 to 418.4 and 62 average annual cases over 2018-2022.
- CI*Rank ⋔ : 36 (7, 46)
- Recent Trend : The trend is because the trend is 0.2 with a 95% confidence interval from -1.1 to 1.5.
Allendale County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 365.8 with a 95% confidence interval from 297.3 to 447.9 and 23 average annual cases over 2018-2022.
- CI*Rank ⋔ : 37 (1, 46)
- Recent Trend : The trend is because the trend is -0.2 with a 95% confidence interval from -1.6 to 1.3.
Lancaster County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 360.6 with a 95% confidence interval from 340.4 to 381.9 and 264 average annual cases over 2018-2022.
- CI*Rank ⋔ : 38 (29, 44)
- Recent Trend : The trend is because the trend is -8.8 with a 95% confidence interval from -12.1 to -4.3.
Aiken County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 360.3 with a 95% confidence interval from 344.5 to 376.6 and 442 average annual cases over 2018-2022.
- CI*Rank ⋔ : 39 (31, 44)
- Recent Trend : The trend is because the trend is 1.9 with a 95% confidence interval from -2.1 to 5.0.
Edgefield County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 356.2 with a 95% confidence interval from 315.2 to 401.5 and 63 average annual cases over 2018-2022.
- CI*Rank ⋔ : 40 (17, 46)
- Recent Trend : The trend is because the trend is -0.3 with a 95% confidence interval from -2.0 to 1.4.
Williamsburg County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 352.7 with a 95% confidence interval from 317.3 to 391.3 and 85 average annual cases over 2018-2022.
- CI*Rank ⋔ : 41 (22, 46)
- Recent Trend : The trend is because the trend is -10.1 with a 95% confidence interval from -17.3 to -1.8.
Lee County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 334.8 with a 95% confidence interval from 286.3 to 389.8 and 40 average annual cases over 2018-2022.
- CI*Rank ⋔ : 42 (21, 46)
- Recent Trend : The trend is because the trend is -0.9 with a 95% confidence interval from -2.5 to 0.6.
Barnwell County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 332.9 with a 95% confidence interval from 291.3 to 379.3 and 51 average annual cases over 2018-2022.
- CI*Rank ⋔ : 43 (27, 46)
- Recent Trend : The trend is because the trend is 0.1 with a 95% confidence interval from -1.7 to 1.8.
Jasper County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 329.5 with a 95% confidence interval from 292.9 to 369.8 and 72 average annual cases over 2018-2022.
- CI*Rank ⋔ : 44 (31, 46)
- Recent Trend : The trend is because the trend is -5.7 with a 95% confidence interval from -11.4 to -2.1.
Saluda County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 326.2 with a 95% confidence interval from 281.4 to 376.7 and 44 average annual cases over 2018-2022.
- CI*Rank ⋔ : 45 (25, 46)
- Recent Trend : The trend is because the trend is -0.4 with a 95% confidence interval from -2.2 to 1.5.
Calhoun County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 317.1 with a 95% confidence interval from 268.4 to 373.1 and 36 average annual cases over 2018-2022.
- CI*Rank ⋔ : 46 (29, 46)
- Recent Trend : The trend is because the trend is -1.0 with a 95% confidence interval from -3.7 to 1.6.
Notes:
Created by statecancerprofiles.cancer.gov on 03/19/2026 10:02 am.
State Cancer Registries may provide more current or more local data.
Trend
Rising when 95% confidence interval of average annual percent change is above 0.
Stable when 95% confidence interval of average annual percent change includes 0.
Falling when 95% confidence interval of average annual percent change is below 0.
Rising when 95% confidence interval of average annual percent change is above 0.
Stable when 95% confidence interval of average annual percent change includes 0.
Falling when 95% confidence interval of average annual percent change is below 0.
† Incidence rates (cases per 100,000 population per year) are age-adjusted to the 2000 US standard population (SEER areas use 20 age groups and NPCR areas use 19 age groups). Rates are for invasive cancer only (except for bladder cancer which is invasive and in situ) or unless otherwise specified. Rates calculated using SEER*Stat. Population counts for denominators are based on Census populations as modified by NCI. The US Population Data File is used for SEER and NPCR incidence rates.
‡ Incidence data come from different sources. The Average Annual Percent Change (AAPC) is based on the APCs calculated by Joinpoint. Due to data availability issues, the time period used in the calculation of the joinpoint regression model may differ for selected counties.
Rates and trends are computed using different standards for malignancy. For more information see malignant.html.
^ All Stages refers to any stage. Due to changes in stage coding, Combined Summary Stage with Expanded Regional Codes (2004+) is used for data from Surveillance, Epidemiology, and End Results (SEER) databases and Merged Summary Stage is used for data from National Program of Cancer Registries databases. Due to the increased complexity with staging, other staging variables maybe used if necessary.
⋔ Results presented with the CI*Rank statistics help show the usefulness of ranks. For example, ranks for relatively rare diseases or less populated areas may be essentially meaningless because of their large variability, but ranks for more common diseases in densely populated regions can be very useful. The rates used in CI*Rank are all age-adjusted to the 2000 US standard population using 19 age groups for SEER and NPCR areas. More information about methodology can be found on the CI*Rank website.
Φ Rural–urban county classifications are based on the 2023 USDA Rural–Urban Continuum Codes (except for Connecticut Counties which use 2013 codes). State-level cancer rates for rural areas are calculated using cancer cases registered exclusively in rural counties, while state-level cancer rates for urban areas are calculated using cases registered exclusively in urban counties.
1 Source: National Program of Cancer Registries and Surveillance, Epidemiology, and End Results SEER*Stat Database - United States Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute. Based on the 2024 submission.
2 Source: National Program of Cancer Registries SEER*Stat Database - United States Department of Health and Human Services, Centers for Disease Control and Prevention (based on the 2024 submission).
Data for United States does not include Puerto Rico.


