Interpretation of Incidence Rates Data
Incidence Rate Report for South Carolina by County
All Cancer Sites (All Stages^), 2018-2022
All Races (includes Hispanic), Both Sexes, All Ages
Sorted by Recentaapc
Explanation of Column HeadersIncidence Rate (95% Confidence Interval) - The incidence rate is based upon 100,000 people and is an annual rate (or average annual rate) based on the time period indicated. Rates are age-adjusted by 5-year age groups to the 2000 U.S. standard million population.
Recent Trends - This is an interpretation of the AAPC/APC:
- Rising when 95% confidence interval of AAPC/APC is above 0.
- Stable when 95% confidence interval of AAPC/APC includes 0.
- Falling when 95% confidence interval of AAPC/APC is below 0.
AAPC/APC (95% Confidence Interval) - the change in rate over time
- Average Annual Percent Change - AAPCs are based upon APCs that were calculated by Joinpoint Regression Program
- Annual Percent Change - APCs calculated in SEER*Stat.
Other Notes
- Larger confidence intervals indicate less stability of the data. This is often due to low counts that are not quite low enough to be suppressed.
- Data is currently being suppressed if there are fewer than 16 counts for the time period.
Line by Line Interpretation of the Report
South Carolina2
- 2023 Rural-Urban Continuum Codes Φ : N/A
- Rate : The incidence rate is 438.4 with a 95% confidence interval from 436.1 to 440.7 and 29,379 average annual cases over 2018-2022.
- CI*Rank ⋔ : N/A
- Recent Trend : The trend is because the trend is -1.3 with a 95% confidence interval from -2.0 to -0.8.
US (SEER+NPCR)1
- 2023 Rural-Urban Continuum Codes Φ : N/A
- Rate : The incidence rate is 448.6 with a 95% confidence interval from 448.3 to 448.9 and 1,821,045 average annual cases over 2018-2022.
- CI*Rank ⋔ : N/A
- Recent Trend : The trend is because the trend is -1.0 with a 95% confidence interval from -1.6 to -0.5.
Calhoun County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 349.3 with a 95% confidence interval from 312.7 to 389.6 and 77 average annual cases over 2018-2022.
- CI*Rank ⋔ : 43 (35, 46)
- Recent Trend : The trend is because the trend is -15.1 with a 95% confidence interval from -25.8 to -2.7.
Jasper County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 343.4 with a 95% confidence interval from 317.6 to 371.0 and 152 average annual cases over 2018-2022.
- CI*Rank ⋔ : 45 (41, 46)
- Recent Trend : The trend is because the trend is -10.2 with a 95% confidence interval from -16.1 to -6.4.
Saluda County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 342.1 with a 95% confidence interval from 310.7 to 376.2 and 95 average annual cases over 2018-2022.
- CI*Rank ⋔ : 46 (39, 46)
- Recent Trend : The trend is because the trend is -9.7 with a 95% confidence interval from -17.1 to -6.2.
Williamsburg County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 412.3 with a 95% confidence interval from 384.9 to 441.4 and 187 average annual cases over 2018-2022.
- CI*Rank ⋔ : 36 (15, 42)
- Recent Trend : The trend is because the trend is -9.2 with a 95% confidence interval from -14.0 to -3.9.
Lancaster County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 391.7 with a 95% confidence interval from 376.7 to 407.3 and 554 average annual cases over 2018-2022.
- CI*Rank ⋔ : 38 (32, 43)
- Recent Trend : The trend is because the trend is -6.6 with a 95% confidence interval from -11.1 to -3.4.
Chesterfield County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 414.7 with a 95% confidence interval from 390.9 to 439.6 and 248 average annual cases over 2018-2022.
- CI*Rank ⋔ : 35 (17, 41)
- Recent Trend : The trend is because the trend is -6.3 with a 95% confidence interval from -10.7 to -0.9.
Lee County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 377.5 with a 95% confidence interval from 341.3 to 416.8 and 88 average annual cases over 2018-2022.
- CI*Rank ⋔ : 41 (26, 46)
- Recent Trend : The trend is because the trend is -5.0 with a 95% confidence interval from -14.5 to -1.7.
Cherokee County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 462.2 with a 95% confidence interval from 439.5 to 485.8 and 331 average annual cases over 2018-2022.
- CI*Rank ⋔ : 12 (1, 31)
- Recent Trend : The trend is because the trend is -4.7 with a 95% confidence interval from -9.8 to -0.1.
Georgetown County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 460.8 with a 95% confidence interval from 440.6 to 481.8 and 513 average annual cases over 2018-2022.
- CI*Rank ⋔ : 13 (2, 29)
- Recent Trend : The trend is because the trend is -4.7 with a 95% confidence interval from -7.8 to -0.8.
Laurens County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 439.0 with a 95% confidence interval from 419.2 to 459.5 and 402 average annual cases over 2018-2022.
- CI*Rank ⋔ : 25 (8, 35)
- Recent Trend : The trend is because the trend is -4.6 with a 95% confidence interval from -8.5 to -0.7.
Berkeley County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 425.4 with a 95% confidence interval from 413.7 to 437.2 and 1,088 average annual cases over 2018-2022.
- CI*Rank ⋔ : 31 (21, 36)
- Recent Trend : The trend is because the trend is -3.2 with a 95% confidence interval from -5.4 to -0.9.
Richland County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 397.4 with a 95% confidence interval from 388.8 to 406.1 and 1,740 average annual cases over 2018-2022.
- CI*Rank ⋔ : 37 (33, 41)
- Recent Trend : The trend is because the trend is -3.0 with a 95% confidence interval from -5.3 to -1.6.
York County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 445.1 with a 95% confidence interval from 434.6 to 455.8 and 1,443 average annual cases over 2018-2022.
- CI*Rank ⋔ : 20 (11, 30)
- Recent Trend : The trend is because the trend is -3.0 with a 95% confidence interval from -4.9 to -1.7.
Sumter County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 434.5 with a 95% confidence interval from 418.0 to 451.5 and 563 average annual cases over 2018-2022.
- CI*Rank ⋔ : 26 (13, 35)
- Recent Trend : The trend is because the trend is -2.6 with a 95% confidence interval from -8.7 to -0.1.
Beaufort County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 390.3 with a 95% confidence interval from 379.6 to 401.3 and 1,246 average annual cases over 2018-2022.
- CI*Rank ⋔ : 40 (34, 43)
- Recent Trend : The trend is because the trend is -1.5 with a 95% confidence interval from -1.8 to -1.1.
Kershaw County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 439.1 with a 95% confidence interval from 419.1 to 460.0 and 390 average annual cases over 2018-2022.
- CI*Rank ⋔ : 24 (8, 36)
- Recent Trend : The trend is because the trend is -1.1 with a 95% confidence interval from -1.5 to -0.7.
Horry County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 429.7 with a 95% confidence interval from 421.4 to 438.1 and 2,468 average annual cases over 2018-2022.
- CI*Rank ⋔ : 28 (21, 35)
- Recent Trend : The trend is because the trend is -0.9 with a 95% confidence interval from -1.3 to -0.4.
Bamberg County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 423.6 with a 95% confidence interval from 382.2 to 468.8 and 88 average annual cases over 2018-2022.
- CI*Rank ⋔ : 33 (3, 43)
- Recent Trend : The trend is because the trend is -0.8 with a 95% confidence interval from -1.4 to -0.2.
Charleston County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 453.0 with a 95% confidence interval from 444.5 to 461.6 and 2,314 average annual cases over 2018-2022.
- CI*Rank ⋔ : 17 (9, 25)
- Recent Trend : The trend is because the trend is -0.8 with a 95% confidence interval from -1.1 to -0.4.
Edgefield County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 345.0 with a 95% confidence interval from 317.7 to 374.3 and 128 average annual cases over 2018-2022.
- CI*Rank ⋔ : 44 (39, 46)
- Recent Trend : The trend is because the trend is -0.8 with a 95% confidence interval from -2.0 to 0.4.
Fairfield County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 416.9 with a 95% confidence interval from 383.6 to 452.5 and 138 average annual cases over 2018-2022.
- CI*Rank ⋔ : 34 (10, 43)
- Recent Trend : The trend is because the trend is -0.8 with a 95% confidence interval from -1.4 to -0.1.
Anderson County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 448.3 with a 95% confidence interval from 436.7 to 460.2 and 1,203 average annual cases over 2018-2022.
- CI*Rank ⋔ : 19 (9, 29)
- Recent Trend : The trend is because the trend is -0.7 with a 95% confidence interval from -1.0 to -0.3.
Barnwell County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 376.4 with a 95% confidence interval from 343.7 to 411.6 and 106 average annual cases over 2018-2022.
- CI*Rank ⋔ : 42 (29, 46)
- Recent Trend : The trend is because the trend is -0.7 with a 95% confidence interval from -1.9 to 0.4.
Aiken County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 390.5 with a 95% confidence interval from 378.8 to 402.5 and 923 average annual cases over 2018-2022.
- CI*Rank ⋔ : 39 (33, 43)
- Recent Trend : The trend is because the trend is -0.6 with a 95% confidence interval from -1.2 to 0.1.
Florence County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 459.9 with a 95% confidence interval from 445.3 to 474.8 and 807 average annual cases over 2018-2022.
- CI*Rank ⋔ : 14 (4, 26)
- Recent Trend : The trend is because the trend is -0.6 with a 95% confidence interval from -2.3 to 0.0.
Newberry County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 427.4 with a 95% confidence interval from 401.7 to 454.5 and 227 average annual cases over 2018-2022.
- CI*Rank ⋔ : 29 (9, 40)
- Recent Trend : The trend is because the trend is -0.6 with a 95% confidence interval from -1.3 to 0.0.
Oconee County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 464.1 with a 95% confidence interval from 446.1 to 482.7 and 581 average annual cases over 2018-2022.
- CI*Rank ⋔ : 9 (2, 26)
- Recent Trend : The trend is because the trend is -0.6 with a 95% confidence interval from -1.0 to -0.1.
Colleton County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 494.2 with a 95% confidence interval from 466.8 to 522.9 and 271 average annual cases over 2018-2022.
- CI*Rank ⋔ : 1 (1, 17)
- Recent Trend : The trend is because the trend is -0.5 with a 95% confidence interval from -1.2 to 0.2.
Lexington County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 441.5 with a 95% confidence interval from 431.7 to 451.6 and 1,607 average annual cases over 2018-2022.
- CI*Rank ⋔ : 23 (14, 31)
- Recent Trend : The trend is because the trend is -0.4 with a 95% confidence interval from -0.9 to 0.0.
Marlboro County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 443.7 with a 95% confidence interval from 412.4 to 476.8 and 161 average annual cases over 2018-2022.
- CI*Rank ⋔ : 22 (2, 38)
- Recent Trend : The trend is because the trend is -0.4 with a 95% confidence interval from -1.3 to 0.5.
Spartanburg County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 462.4 with a 95% confidence interval from 452.8 to 472.2 and 1,857 average annual cases over 2018-2022.
- CI*Rank ⋔ : 11 (5, 20)
- Recent Trend : The trend is because the trend is -0.4 with a 95% confidence interval from -0.7 to -0.1.
Abbeville County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 424.2 with a 95% confidence interval from 392.9 to 457.6 and 155 average annual cases over 2018-2022.
- CI*Rank ⋔ : 32 (6, 42)
- Recent Trend : The trend is because the trend is -0.3 with a 95% confidence interval from -1.3 to 0.6.
Greenville County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 472.4 with a 95% confidence interval from 464.7 to 480.2 and 3,005 average annual cases over 2018-2022.
- CI*Rank ⋔ : 6 (3, 14)
- Recent Trend : The trend is because the trend is -0.3 with a 95% confidence interval from -0.5 to -0.1.
McCormick County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 444.8 with a 95% confidence interval from 397.7 to 497.8 and 92 average annual cases over 2018-2022.
- CI*Rank ⋔ : 21 (1, 42)
- Recent Trend : The trend is because the trend is -0.3 with a 95% confidence interval from -1.3 to 0.7.
Orangeburg County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 472.1 with a 95% confidence interval from 453.7 to 491.1 and 556 average annual cases over 2018-2022.
- CI*Rank ⋔ : 7 (1, 23)
- Recent Trend : The trend is because the trend is -0.3 with a 95% confidence interval from -1.0 to 0.3.
Pickens County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 464.0 with a 95% confidence interval from 448.5 to 479.8 and 733 average annual cases over 2018-2022.
- CI*Rank ⋔ : 10 (3, 24)
- Recent Trend : The trend is because the trend is -0.3 with a 95% confidence interval from -0.6 to 0.1.
Darlington County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 433.3 with a 95% confidence interval from 413.0 to 454.4 and 375 average annual cases over 2018-2022.
- CI*Rank ⋔ : 27 (11, 36)
- Recent Trend : The trend is because the trend is -0.2 with a 95% confidence interval from -0.8 to 0.4.
Hampton County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 457.1 with a 95% confidence interval from 419.5 to 497.6 and 116 average annual cases over 2018-2022.
- CI*Rank ⋔ : 15 (1, 36)
- Recent Trend : The trend is because the trend is -0.2 with a 95% confidence interval from -1.3 to 0.9.
Allendale County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 427.1 with a 95% confidence interval from 373.4 to 487.1 and 50 average annual cases over 2018-2022.
- CI*Rank ⋔ : 30 (1, 44)
- Recent Trend : The trend is because the trend is 0.0 with a 95% confidence interval from -1.2 to 1.2.
Greenwood County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 489.5 with a 95% confidence interval from 468.7 to 511.0 and 448 average annual cases over 2018-2022.
- CI*Rank ⋔ : 3 (1, 15)
- Recent Trend : The trend is because the trend is 0.0 with a 95% confidence interval from -0.5 to 0.6.
Clarendon County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 451.1 with a 95% confidence interval from 423.2 to 480.7 and 227 average annual cases over 2018-2022.
- CI*Rank ⋔ : 18 (2, 35)
- Recent Trend : The trend is because the trend is 0.1 with a 95% confidence interval from -0.9 to 1.0.
Dillon County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 484.8 with a 95% confidence interval from 452.1 to 519.4 and 175 average annual cases over 2018-2022.
- CI*Rank ⋔ : 4 (1, 27)
- Recent Trend : The trend is because the trend is 0.1 with a 95% confidence interval from -0.8 to 1.1.
Marion County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 455.2 with a 95% confidence interval from 424.9 to 487.1 and 189 average annual cases over 2018-2022.
- CI*Rank ⋔ : 16 (1, 35)
- Recent Trend : The trend is because the trend is 0.1 with a 95% confidence interval from -0.6 to 0.8.
Chester County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 492.6 with a 95% confidence interval from 462.5 to 524.4 and 217 average annual cases over 2018-2022.
- CI*Rank ⋔ : 2 (1, 21)
- Recent Trend : The trend is because the trend is 0.2 with a 95% confidence interval from -0.4 to 0.8.
Union County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 482.2 with a 95% confidence interval from 450.2 to 516.0 and 191 average annual cases over 2018-2022.
- CI*Rank ⋔ : 5 (1, 26)
- Recent Trend : The trend is because the trend is 0.2 with a 95% confidence interval from -0.6 to 1.0.
Dorchester County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 466.5 with a 95% confidence interval from 452.2 to 481.2 and 854 average annual cases over 2018-2022.
- CI*Rank ⋔ : 8 (2, 22)
- Recent Trend : The trend is because the trend is 2.5 with a 95% confidence interval from 0.5 to 4.2.
Notes:
Created by statecancerprofiles.cancer.gov on 03/13/2026 6:00 pm.
State Cancer Registries may provide more current or more local data.
Trend
Rising when 95% confidence interval of average annual percent change is above 0.
Stable when 95% confidence interval of average annual percent change includes 0.
Falling when 95% confidence interval of average annual percent change is below 0.
Rising when 95% confidence interval of average annual percent change is above 0.
Stable when 95% confidence interval of average annual percent change includes 0.
Falling when 95% confidence interval of average annual percent change is below 0.
† Incidence rates (cases per 100,000 population per year) are age-adjusted to the 2000 US standard population (SEER areas use 20 age groups and NPCR areas use 19 age groups). Rates are for invasive cancer only (except for bladder cancer which is invasive and in situ) or unless otherwise specified. Rates calculated using SEER*Stat. Population counts for denominators are based on Census populations as modified by NCI. The US Population Data File is used for SEER and NPCR incidence rates.
‡ Incidence data come from different sources. The Average Annual Percent Change (AAPC) is based on the APCs calculated by Joinpoint. Due to data availability issues, the time period used in the calculation of the joinpoint regression model may differ for selected counties.
Rates and trends are computed using different standards for malignancy. For more information see malignant.html.
^ All Stages refers to any stage. Due to changes in stage coding, Combined Summary Stage with Expanded Regional Codes (2004+) is used for data from Surveillance, Epidemiology, and End Results (SEER) databases and Merged Summary Stage is used for data from National Program of Cancer Registries databases. Due to the increased complexity with staging, other staging variables maybe used if necessary.
⋔ Results presented with the CI*Rank statistics help show the usefulness of ranks. For example, ranks for relatively rare diseases or less populated areas may be essentially meaningless because of their large variability, but ranks for more common diseases in densely populated regions can be very useful. The rates used in CI*Rank are all age-adjusted to the 2000 US standard population using 19 age groups for SEER and NPCR areas. More information about methodology can be found on the CI*Rank website.
Φ Rural–urban county classifications are based on the 2023 USDA Rural–Urban Continuum Codes (except for Connecticut Counties which use 2013 codes). State-level cancer rates for rural areas are calculated using cancer cases registered exclusively in rural counties, while state-level cancer rates for urban areas are calculated using cases registered exclusively in urban counties.
1 Source: National Program of Cancer Registries and Surveillance, Epidemiology, and End Results SEER*Stat Database - United States Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute. Based on the 2024 submission.
2 Source: National Program of Cancer Registries SEER*Stat Database - United States Department of Health and Human Services, Centers for Disease Control and Prevention (based on the 2024 submission).
Data for United States does not include Puerto Rico.


