Interpretation of Incidence Rates Data
Incidence Rate Report for South Carolina by County
All Cancer Sites (All Stages^), 2018-2022
White Non-Hispanic, Both Sexes, All Ages
Sorted by Recentaapc
Explanation of Column HeadersIncidence Rate (95% Confidence Interval) - The incidence rate is based upon 100,000 people and is an annual rate (or average annual rate) based on the time period indicated. Rates are age-adjusted by 5-year age groups to the 2000 U.S. standard million population.
Recent Trends - This is an interpretation of the AAPC/APC:
- Rising when 95% confidence interval of AAPC/APC is above 0.
- Stable when 95% confidence interval of AAPC/APC includes 0.
- Falling when 95% confidence interval of AAPC/APC is below 0.
AAPC/APC (95% Confidence Interval) - the change in rate over time
- Average Annual Percent Change - AAPCs are based upon APCs that were calculated by Joinpoint Regression Program
- Annual Percent Change - APCs calculated in SEER*Stat.
Other Notes
- Larger confidence intervals indicate less stability of the data. This is often due to low counts that are not quite low enough to be suppressed.
- Data is currently being suppressed if there are fewer than 16 counts for the time period.
Line by Line Interpretation of the Report
South Carolina2
- 2023 Rural-Urban Continuum Codes Φ : N/A
- Rate : The incidence rate is 447.4 with a 95% confidence interval from 444.6 to 450.2 and 21,642 average annual cases over 2018-2022.
- CI*Rank ⋔ : N/A
- Recent Trend : The trend is because the trend is -1.3 with a 95% confidence interval from -2.4 to -0.8.
US (SEER+NPCR) § 1
- 2023 Rural-Urban Continuum Codes Φ : N/A
- Rate : The incidence rate is 467.1 with a 95% confidence interval from 466.7 to 467.5 and 1,354,187 average annual cases over 2018-2022.
- CI*Rank ⋔ : N/A
- Recent Trend : The trend is because the trend is -1.1 with a 95% confidence interval from -1.7 to -0.7.
Chester County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 505.7 with a 95% confidence interval from 467.8 to 546.1 and 146 average annual cases over 2018-2022.
- CI*Rank ⋔ : 2 (1, 24)
- Recent Trend : The trend is because the trend is 6.5 with a 95% confidence interval from 0.2 to 11.3.
McCormick County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 501.0 with a 95% confidence interval from 422.6 to 595.4 and 63 average annual cases over 2018-2022.
- CI*Rank ⋔ : 4 (1, 40)
- Recent Trend : The trend is because the trend is 0.8 with a 95% confidence interval from -0.5 to 2.1.
Dillon County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 479.6 with a 95% confidence interval from 435.3 to 527.7 and 95 average annual cases over 2018-2022.
- CI*Rank ⋔ : 11 (1, 34)
- Recent Trend : The trend is because the trend is 0.5 with a 95% confidence interval from -0.6 to 1.6.
Clarendon County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 487.1 with a 95% confidence interval from 447.3 to 530.2 and 138 average annual cases over 2018-2022.
- CI*Rank ⋔ : 7 (1, 31)
- Recent Trend : The trend is because the trend is 0.4 with a 95% confidence interval from -0.8 to 1.7.
Greenwood County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 495.2 with a 95% confidence interval from 469.6 to 522.0 and 320 average annual cases over 2018-2022.
- CI*Rank ⋔ : 5 (1, 21)
- Recent Trend : The trend is because the trend is 0.3 with a 95% confidence interval from -0.5 to 1.1.
Marion County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 491.2 with a 95% confidence interval from 443.6 to 543.3 and 92 average annual cases over 2018-2022.
- CI*Rank ⋔ : 6 (1, 34)
- Recent Trend : The trend is because the trend is 0.2 with a 95% confidence interval from -0.8 to 1.1.
Union County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 503.5 with a 95% confidence interval from 463.8 to 546.0 and 136 average annual cases over 2018-2022.
- CI*Rank ⋔ : 3 (1, 27)
- Recent Trend : The trend is because the trend is 0.2 with a 95% confidence interval from -0.5 to 0.9.
Hampton County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 474.7 with a 95% confidence interval from 417.6 to 538.3 and 56 average annual cases over 2018-2022.
- CI*Rank ⋔ : 14 (1, 40)
- Recent Trend : The trend is because the trend is 0.1 with a 95% confidence interval from -0.9 to 1.1.
Darlington County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 424.8 with a 95% confidence interval from 399.0 to 452.1 and 224 average annual cases over 2018-2022.
- CI*Rank ⋔ : 33 (16, 41)
- Recent Trend : The trend is because the trend is -0.1 with a 95% confidence interval from -0.8 to 0.6.
Pickens County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 471.8 with a 95% confidence interval from 455.3 to 488.8 and 673 average annual cases over 2018-2022.
- CI*Rank ⋔ : 15 (4, 26)
- Recent Trend : The trend is because the trend is -0.1 with a 95% confidence interval from -0.5 to 0.3.
Spartanburg County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 480.1 with a 95% confidence interval from 468.8 to 491.7 and 1,466 average annual cases over 2018-2022.
- CI*Rank ⋔ : 10 (3, 19)
- Recent Trend : The trend is because the trend is -0.1 with a 95% confidence interval from -0.4 to 0.2.
Allendale County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 438.9 with a 95% confidence interval from 335.6 to 575.7 and 16 average annual cases over 2018-2022.
- CI*Rank ⋔ : 27 (1, 46)
- Recent Trend : The trend is because the trend is -0.2 with a 95% confidence interval from -3.1 to 2.6.
Florence County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 453.9 with a 95% confidence interval from 435.1 to 473.5 and 475 average annual cases over 2018-2022.
- CI*Rank ⋔ : 21 (8, 32)
- Recent Trend : The trend is because the trend is -0.2 with a 95% confidence interval from -0.9 to 0.6.
Georgetown County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 454.0 with a 95% confidence interval from 430.0 to 479.4 and 382 average annual cases over 2018-2022.
- CI*Rank ⋔ : 20 (5, 33)
- Recent Trend : The trend is because the trend is -0.2 with a 95% confidence interval from -1.1 to 0.7.
Greenville County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 480.2 with a 95% confidence interval from 471.3 to 489.3 and 2,357 average annual cases over 2018-2022.
- CI*Rank ⋔ : 9 (4, 17)
- Recent Trend : The trend is because the trend is -0.2 with a 95% confidence interval from -0.4 to 0.0.
Lexington County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 451.7 with a 95% confidence interval from 440.7 to 463.0 and 1,367 average annual cases over 2018-2022.
- CI*Rank ⋔ : 24 (13, 30)
- Recent Trend : The trend is because the trend is -0.2 with a 95% confidence interval from -0.7 to 0.2.
Orangeburg County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 478.9 with a 95% confidence interval from 449.4 to 510.1 and 234 average annual cases over 2018-2022.
- CI*Rank ⋔ : 12 (1, 29)
- Recent Trend : The trend is because the trend is -0.2 with a 95% confidence interval from -1.0 to 0.5.
Newberry County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 422.5 with a 95% confidence interval from 391.0 to 456.1 and 157 average annual cases over 2018-2022.
- CI*Rank ⋔ : 34 (13, 42)
- Recent Trend : The trend is because the trend is -0.3 with a 95% confidence interval from -0.9 to 0.3.
Abbeville County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 401.9 with a 95% confidence interval from 366.3 to 440.5 and 108 average annual cases over 2018-2022.
- CI*Rank ⋔ : 38 (19, 43)
- Recent Trend : The trend is because the trend is -0.4 with a 95% confidence interval from -1.6 to 0.7.
Fairfield County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 436.3 with a 95% confidence interval from 383.1 to 496.2 and 67 average annual cases over 2018-2022.
- CI*Rank ⋔ : 29 (2, 43)
- Recent Trend : The trend is because the trend is -0.4 with a 95% confidence interval from -1.3 to 0.4.
Lee County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 377.8 with a 95% confidence interval from 319.5 to 445.5 and 35 average annual cases over 2018-2022.
- CI*Rank ⋔ : 42 (13, 46)
- Recent Trend : The trend is because the trend is -0.4 with a 95% confidence interval from -2.2 to 1.2.
Oconee County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 470.7 with a 95% confidence interval from 451.3 to 490.8 and 532 average annual cases over 2018-2022.
- CI*Rank ⋔ : 16 (4, 28)
- Recent Trend : The trend is because the trend is -0.4 with a 95% confidence interval from -0.9 to 0.1.
Colleton County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 513.3 with a 95% confidence interval from 477.8 to 551.0 and 174 average annual cases over 2018-2022.
- CI*Rank ⋔ : 1 (1, 19)
- Recent Trend : The trend is because the trend is -0.5 with a 95% confidence interval from -1.1 to 0.1.
Aiken County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 400.0 with a 95% confidence interval from 386.0 to 414.3 and 712 average annual cases over 2018-2022.
- CI*Rank ⋔ : 39 (31, 42)
- Recent Trend : The trend is because the trend is -0.6 with a 95% confidence interval from -1.3 to 0.2.
Anderson County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 452.8 with a 95% confidence interval from 439.9 to 466.1 and 1,008 average annual cases over 2018-2022.
- CI*Rank ⋔ : 23 (12, 31)
- Recent Trend : The trend is because the trend is -0.6 with a 95% confidence interval from -0.9 to -0.2.
Bamberg County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 427.9 with a 95% confidence interval from 363.5 to 502.4 and 38 average annual cases over 2018-2022.
- CI*Rank ⋔ : 31 (1, 44)
- Recent Trend : The trend is because the trend is -0.7 with a 95% confidence interval from -2.1 to 0.6.
Charleston County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 463.0 with a 95% confidence interval from 452.8 to 473.4 and 1,662 average annual cases over 2018-2022.
- CI*Rank ⋔ : 17 (9, 26)
- Recent Trend : The trend is because the trend is -0.7 with a 95% confidence interval from -1.0 to -0.3.
Dorchester County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 476.9 with a 95% confidence interval from 459.8 to 494.6 and 624 average annual cases over 2018-2022.
- CI*Rank ⋔ : 13 (3, 24)
- Recent Trend : The trend is because the trend is -0.8 with a 95% confidence interval from -1.3 to -0.3.
Horry County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 435.6 with a 95% confidence interval from 426.4 to 445.1 and 2,175 average annual cases over 2018-2022.
- CI*Rank ⋔ : 30 (22, 34)
- Recent Trend : The trend is because the trend is -0.8 with a 95% confidence interval from -1.3 to -0.2.
Marlboro County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 458.8 with a 95% confidence interval from 413.0 to 509.1 and 81 average annual cases over 2018-2022.
- CI*Rank ⋔ : 18 (1, 40)
- Recent Trend : The trend is because the trend is -0.8 with a 95% confidence interval from -2.0 to 0.4.
Barnwell County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 380.3 with a 95% confidence interval from 336.7 to 428.5 and 62 average annual cases over 2018-2022.
- CI*Rank ⋔ : 40 (25, 46)
- Recent Trend : The trend is because the trend is -0.9 with a 95% confidence interval from -2.3 to 0.5.
Kershaw County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 443.8 with a 95% confidence interval from 420.0 to 468.7 and 286 average annual cases over 2018-2022.
- CI*Rank ⋔ : 26 (10, 36)
- Recent Trend : The trend is because the trend is -0.9 with a 95% confidence interval from -1.4 to -0.3.
Edgefield County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 338.2 with a 95% confidence interval from 304.1 to 375.6 and 82 average annual cases over 2018-2022.
- CI*Rank ⋔ : 44 (39, 46)
- Recent Trend : The trend is because the trend is -1.0 with a 95% confidence interval from -2.2 to 0.2.
Beaufort County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 402.9 with a 95% confidence interval from 389.9 to 416.3 and 1,054 average annual cases over 2018-2022.
- CI*Rank ⋔ : 37 (31, 42)
- Recent Trend : The trend is because the trend is -1.3 with a 95% confidence interval from -1.8 to -0.9.
Berkeley County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 437.0 with a 95% confidence interval from 422.8 to 451.5 and 778 average annual cases over 2018-2022.
- CI*Rank ⋔ : 28 (18, 35)
- Recent Trend : The trend is because the trend is -2.6 with a 95% confidence interval from -6.2 to -1.2.
Richland County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 403.2 with a 95% confidence interval from 390.8 to 415.8 and 864 average annual cases over 2018-2022.
- CI*Rank ⋔ : 36 (31, 41)
- Recent Trend : The trend is because the trend is -2.9 with a 95% confidence interval from -5.7 to -1.3.
York County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 456.3 with a 95% confidence interval from 444.3 to 468.6 and 1,155 average annual cases over 2018-2022.
- CI*Rank ⋔ : 19 (11, 29)
- Recent Trend : The trend is because the trend is -3.3 with a 95% confidence interval from -5.2 to -1.9.
Sumter County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 453.6 with a 95% confidence interval from 429.7 to 478.6 and 292 average annual cases over 2018-2022.
- CI*Rank ⋔ : 22 (6, 34)
- Recent Trend : The trend is because the trend is -4.3 with a 95% confidence interval from -9.0 to 0.0.
Laurens County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 444.2 with a 95% confidence interval from 420.7 to 468.7 and 298 average annual cases over 2018-2022.
- CI*Rank ⋔ : 25 (9, 35)
- Recent Trend : The trend is because the trend is -5.3 with a 95% confidence interval from -9.4 to -0.7.
Cherokee County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 481.6 with a 95% confidence interval from 455.5 to 508.9 and 275 average annual cases over 2018-2022.
- CI*Rank ⋔ : 8 (1, 26)
- Recent Trend : The trend is because the trend is -5.6 with a 95% confidence interval from -9.6 to -0.4.
Chesterfield County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 425.5 with a 95% confidence interval from 395.7 to 457.3 and 169 average annual cases over 2018-2022.
- CI*Rank ⋔ : 32 (13, 41)
- Recent Trend : The trend is because the trend is -7.0 with a 95% confidence interval from -11.1 to -2.1.
Lancaster County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 405.1 with a 95% confidence interval from 387.4 to 423.5 and 451 average annual cases over 2018-2022.
- CI*Rank ⋔ : 35 (29, 42)
- Recent Trend : The trend is because the trend is -8.2 with a 95% confidence interval from -13.6 to -2.5.
Jasper County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 347.0 with a 95% confidence interval from 310.2 to 388.0 and 92 average annual cases over 2018-2022.
- CI*Rank ⋔ : 43 (35, 46)
- Recent Trend : The trend is because the trend is -12.3 with a 95% confidence interval from -17.0 to -8.8.
Saluda County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 317.6 with a 95% confidence interval from 279.8 to 359.8 and 62 average annual cases over 2018-2022.
- CI*Rank ⋔ : 45 (40, 46)
- Recent Trend : The trend is because the trend is -12.7 with a 95% confidence interval from -25.0 to -6.6.
Williamsburg County2
- 2023 Rural-Urban Continuum Codes Φ : Rural
- Rate : The incidence rate is 378.6 with a 95% confidence interval from 335.6 to 426.6 and 65 average annual cases over 2018-2022.
- CI*Rank ⋔ : 41 (23, 46)
- Recent Trend : The trend is because the trend is -13.2 with a 95% confidence interval from -20.2 to -5.3.
Calhoun County2
- 2023 Rural-Urban Continuum Codes Φ : Urban
- Rate : The incidence rate is 317.1 with a 95% confidence interval from 270.9 to 370.1 and 41 average annual cases over 2018-2022.
- CI*Rank ⋔ : 46 (39, 46)
- Recent Trend : The trend is because the trend is -18.9 with a 95% confidence interval from -28.8 to -6.7.
Notes:
Created by statecancerprofiles.cancer.gov on 03/15/2026 12:39 pm.
State Cancer Registries may provide more current or more local data.
Trend
Rising when 95% confidence interval of average annual percent change is above 0.
Stable when 95% confidence interval of average annual percent change includes 0.
Falling when 95% confidence interval of average annual percent change is below 0.
Rising when 95% confidence interval of average annual percent change is above 0.
Stable when 95% confidence interval of average annual percent change includes 0.
Falling when 95% confidence interval of average annual percent change is below 0.
† Incidence rates (cases per 100,000 population per year) are age-adjusted to the 2000 US standard population (SEER areas use 20 age groups and NPCR areas use 19 age groups). Rates are for invasive cancer only (except for bladder cancer which is invasive and in situ) or unless otherwise specified. Rates calculated using SEER*Stat. Population counts for denominators are based on Census populations as modified by NCI. The US Population Data File is used for SEER and NPCR incidence rates.
‡ Incidence data come from different sources. The Average Annual Percent Change (AAPC) is based on the APCs calculated by Joinpoint. Due to data availability issues, the time period used in the calculation of the joinpoint regression model may differ for selected counties.
Rates and trends are computed using different standards for malignancy. For more information see malignant.html.
^ All Stages refers to any stage. Due to changes in stage coding, Combined Summary Stage with Expanded Regional Codes (2004+) is used for data from Surveillance, Epidemiology, and End Results (SEER) databases and Merged Summary Stage is used for data from National Program of Cancer Registries databases. Due to the increased complexity with staging, other staging variables maybe used if necessary.
⋔ Results presented with the CI*Rank statistics help show the usefulness of ranks. For example, ranks for relatively rare diseases or less populated areas may be essentially meaningless because of their large variability, but ranks for more common diseases in densely populated regions can be very useful. The rates used in CI*Rank are all age-adjusted to the 2000 US standard population using 19 age groups for SEER and NPCR areas. More information about methodology can be found on the CI*Rank website.
Φ Rural–urban county classifications are based on the 2023 USDA Rural–Urban Continuum Codes (except for Connecticut Counties which use 2013 codes). State-level cancer rates for rural areas are calculated using cancer cases registered exclusively in rural counties, while state-level cancer rates for urban areas are calculated using cases registered exclusively in urban counties.
1 Source: National Program of Cancer Registries and Surveillance, Epidemiology, and End Results SEER*Stat Database - United States Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute. Based on the 2024 submission.
2 Source: National Program of Cancer Registries SEER*Stat Database - United States Department of Health and Human Services, Centers for Disease Control and Prevention (based on the 2024 submission).
Data for United States does not include Puerto Rico.


