State Cancer Profiles

Interpretation of Incidence Rates Data

Incidence Rate Report by State

Liver & Bile Duct (Late Stage^), 2018-2022

All Races (includes Hispanic), Both Sexes, All Ages

Sorted by Rate

Explanation of Column Headers
Incidence Rate (95% Confidence Interval) - The incidence rate is based upon 100,000 people and is an annual rate (or average annual rate) based on the time period indicated. Rates are age-adjusted by 5-year age groups to the 2000 U.S. standard million population.

Percent of Cases with Late Stage - This is the number of late stages cases compared to the number of cases for all stages.

Other Notes

• Larger confidence intervals indicate less stability of the data. This is often due to low counts that are not quite low enough to be suppressed.
• Data is currently being suppressed if there are fewer than 16 counts for the time period.

Line by Line Interpretation of the Report

US (SEER+NPCR)¹

• Rate : The incidence rate is 3.7 with a 95% confidence interval from 3.7 to 3.7 and 15,888 average annual cases over 2018-2022.
• CI*Rank ⋔ : N/A
• Percent of Cases with Late Stage : 42.7

Puerto Rico²

• Rate : The incidence rate is 1.9 with a 95% confidence interval from 1.8 to 2.1 and 101 average annual cases over 2018-2022.
• CI*Rank ⋔ : N/A
• Percent of Cases with Late Stage : 25.0

Wyoming²

• Rate : The incidence rate is 2.0 with a 95% confidence interval from 1.6 to 2.5 and 17 average annual cases over 2018-2022.
• CI*Rank ⋔ : 51 (48, 51)
• Percent of Cases with Late Stage : 41.9

New Hampshire²

• Rate : The incidence rate is 2.7 with a 95% confidence interval from 2.4 to 3.1 and 56 average annual cases over 2018-2022.
• CI*Rank ⋔ : 50 (32, 51)
• Percent of Cases with Late Stage : 41.0

Nevada²

• Rate : The incidence rate is 2.8 with a 95% confidence interval from 2.5 to 3.0 and 112 average annual cases over 2018-2022.
• CI*Rank ⋔ : 49 (36, 50)
• Percent of Cases with Late Stage : 38.0

Colorado²

• Rate : The incidence rate is 2.8 with a 95% confidence interval from 2.6 to 3.0 and 197 average annual cases over 2018-2022.
• CI*Rank ⋔ : 48 (36, 50)
• Percent of Cases with Late Stage : 39.9

Nebraska²

• Rate : The incidence rate is 2.8 with a 95% confidence interval from 2.5 to 3.2 and 69 average annual cases over 2018-2022.
• CI*Rank ⋔ : 47 (30, 50)
• Percent of Cases with Late Stage : 46.2

Vermont²

• Rate : The incidence rate is 2.8 with a 95% confidence interval from 2.4 to 3.4 and 29 average annual cases over 2018-2022.
• CI*Rank ⋔ : 46 (21, 51)
• Percent of Cases with Late Stage : 48.1

Alabama²

• Rate : The incidence rate is 2.9 with a 95% confidence interval from 2.7 to 3.1 and 198 average annual cases over 2018-2022.
• CI*Rank ⋔ : 45 (35, 50)
• Percent of Cases with Late Stage : 33.5

Maine²

• Rate : The incidence rate is 2.9 with a 95% confidence interval from 2.6 to 3.3 and 61 average annual cases over 2018-2022.
• CI*Rank ⋔ : 44 (26, 50)
• Percent of Cases with Late Stage : 40.0

New Mexico⁷

• Rate : The incidence rate is 2.9 with a 95% confidence interval from 2.6 to 3.2 and 86 average annual cases over 2018-2022.
• CI*Rank ⋔ : 43 (29, 50)
• Percent of Cases with Late Stage : 30.2

Utah⁷

• Rate : The incidence rate is 2.9 with a 95% confidence interval from 2.7 to 3.2 and 91 average annual cases over 2018-2022.
• CI*Rank ⋔ : 42 (29, 50)
• Percent of Cases with Late Stage : 42.4

Virginia²

• Rate : The incidence rate is 2.9 with a 95% confidence interval from 2.8 to 3.1 and 332 average annual cases over 2018-2022.
• CI*Rank ⋔ : 41 (34, 49)
• Percent of Cases with Late Stage : 40.0

Kansas²

• Rate : The incidence rate is 3.0 with a 95% confidence interval from 2.7 to 3.2 and 111 average annual cases over 2018-2022.
• CI*Rank ⋔ : 40 (28, 50)
• Percent of Cases with Late Stage : 41.3

Arizona²

• Rate : The incidence rate is 3.0 with a 95% confidence interval from 2.8 to 3.2 and 291 average annual cases over 2018-2022.
• CI*Rank ⋔ : 39 (33, 49)
• Percent of Cases with Late Stage : 37.6

Michigan²

• Rate : The incidence rate is 3.1 with a 95% confidence interval from 2.9 to 3.2 and 429 average annual cases over 2018-2022.
• CI*Rank ⋔ : 38 (31, 46)
• Percent of Cases with Late Stage : 42.8

North Dakota²

• Rate : The incidence rate is 3.1 with a 95% confidence interval from 2.6 to 3.7 and 29 average annual cases over 2018-2022.
• CI*Rank ⋔ : 37 (8, 50)
• Percent of Cases with Late Stage : 47.1

Ohio²

• Rate : The incidence rate is 3.1 with a 95% confidence interval from 3.0 to 3.3 and 509 average annual cases over 2018-2022.
• CI*Rank ⋔ : 36 (29, 43)
• Percent of Cases with Late Stage : 41.2

South Dakota²

• Rate : The incidence rate is 3.2 with a 95% confidence interval from 2.8 to 3.7 and 38 average annual cases over 2018-2022.
• CI*Rank ⋔ : 35 (9, 50)
• Percent of Cases with Late Stage : 47.8

Minnesota²

• Rate : The incidence rate is 3.2 with a 95% confidence interval from 3.1 to 3.4 and 235 average annual cases over 2018-2022.
• CI*Rank ⋔ : 34 (23, 43)
• Percent of Cases with Late Stage : 40.4

Montana²

• Rate : The incidence rate is 3.3 with a 95% confidence interval from 2.9 to 3.7 and 52 average annual cases over 2018-2022.
• CI*Rank ⋔ : 33 (9, 50)
• Percent of Cases with Late Stage : 45.2

Wisconsin²

• Rate : The incidence rate is 3.3 with a 95% confidence interval from 3.1 to 3.5 and 265 average annual cases over 2018-2022.
• CI*Rank ⋔ : 32 (22, 41)
• Percent of Cases with Late Stage : 44.1

South Carolina²

• Rate : The incidence rate is 3.3 with a 95% confidence interval from 3.1 to 3.5 and 239 average annual cases over 2018-2022.
• CI*Rank ⋔ : 31 (21, 41)
• Percent of Cases with Late Stage : 41.3

Idaho⁷

• Rate : The incidence rate is 3.3 with a 95% confidence interval from 3.0 to 3.7 and 77 average annual cases over 2018-2022.
• CI*Rank ⋔ : 30 (12, 48)
• Percent of Cases with Late Stage : 43.6

Oregon²

• Rate : The incidence rate is 3.4 with a 95% confidence interval from 3.2 to 3.6 and 199 average annual cases over 2018-2022.
• CI*Rank ⋔ : 29 (15, 39)
• Percent of Cases with Late Stage : 38.6

West Virginia²

• Rate : The incidence rate is 3.4 with a 95% confidence interval from 3.1 to 3.8 and 92 average annual cases over 2018-2022.
• CI*Rank ⋔ : 28 (10, 43)
• Percent of Cases with Late Stage : 41.0

Oklahoma²

• Rate : The incidence rate is 3.5 with a 95% confidence interval from 3.2 to 3.7 and 173 average annual cases over 2018-2022.
• CI*Rank ⋔ : 27 (13, 37)
• Percent of Cases with Late Stage : 36.9

Illinois⁷

• Rate : The incidence rate is 3.5 with a 95% confidence interval from 3.4 to 3.6 and 570 average annual cases over 2018-2022.
• CI*Rank ⋔ : 26 (17, 34)
• Percent of Cases with Late Stage : 42.8

Delaware²

• Rate : The incidence rate is 3.5 with a 95% confidence interval from 3.1 to 4.0 and 51 average annual cases over 2018-2022.
• CI*Rank ⋔ : 25 (5, 46)
• Percent of Cases with Late Stage : 42.2

Iowa⁷

• Rate : The incidence rate is 3.5 with a 95% confidence interval from 3.3 to 3.8 and 151 average annual cases over 2018-2022.
• CI*Rank ⋔ : 24 (9, 37)
• Percent of Cases with Late Stage : 48.0

Maryland²

• Rate : The incidence rate is 3.5 with a 95% confidence interval from 3.4 to 3.7 and 281 average annual cases over 2018-2022.
• CI*Rank ⋔ : 23 (12, 33)
• Percent of Cases with Late Stage : 42.1

New Jersey⁷

• Rate : The incidence rate is 3.6 with a 95% confidence interval from 3.4 to 3.7 and 431 average annual cases over 2018-2022.
• CI*Rank ⋔ : 22 (14, 32)
• Percent of Cases with Late Stage : 44.5

Tennessee²

• Rate : The incidence rate is 3.6 with a 95% confidence interval from 3.4 to 3.8 and 329 average annual cases over 2018-2022.
• CI*Rank ⋔ : 20 (11, 32)
• Percent of Cases with Late Stage : 41.9

Connecticut⁷

• Rate : The incidence rate is 3.6 with a 95% confidence interval from 3.4 to 3.9 and 181 average annual cases over 2018-2022.
• CI*Rank ⋔ : 21 (9, 34)
• Percent of Cases with Late Stage : 44.7

Florida²

• Rate : The incidence rate is 3.6 with a 95% confidence interval from 3.5 to 3.7 and 1,181 average annual cases over 2018-2022.
• CI*Rank ⋔ : 19 (15, 28)
• Percent of Cases with Late Stage : 43.1

Hawaii⁷

• Rate : The incidence rate is 3.7 with a 95% confidence interval from 3.3 to 4.1 and 74 average annual cases over 2018-2022.
• CI*Rank ⋔ : 18 (4, 39)
• Percent of Cases with Late Stage : 39.5

New York⁷

• Rate : The incidence rate is 3.7 with a 95% confidence interval from 3.6 to 3.8 and 990 average annual cases over 2018-2022.
• CI*Rank ⋔ : 17 (10, 24)
• Percent of Cases with Late Stage : 46.1

Indiana²

• Rate : The incidence rate is 3.8 with a 95% confidence interval from 3.6 to 4.0 and 327 average annual cases over 2018-2022.
• CI*Rank ⋔ : 16 (7, 26)
• Percent of Cases with Late Stage : 46.1

Mississippi²

• Rate : The incidence rate is 3.8 with a 95% confidence interval from 3.5 to 4.1 and 149 average annual cases over 2018-2022.
• CI*Rank ⋔ : 15 (5, 30)
• Percent of Cases with Late Stage : 43.8

Pennsylvania²

• Rate : The incidence rate is 3.8 with a 95% confidence interval from 3.7 to 3.9 and 701 average annual cases over 2018-2022.
• CI*Rank ⋔ : 14 (8, 23)
• Percent of Cases with Late Stage : 45.5

Arkansas²

• Rate : The incidence rate is 3.8 with a 95% confidence interval from 3.5 to 4.1 and 151 average annual cases over 2018-2022.
• CI*Rank ⋔ : 13 (5, 30)
• Percent of Cases with Late Stage : 42.4

California⁷

• Rate : The incidence rate is 3.9 with a 95% confidence interval from 3.8 to 4.0 and 1,827 average annual cases over 2018-2022.
• CI*Rank ⋔ : 12 (7, 18)
• Percent of Cases with Late Stage : 40.5

Massachusetts²

• Rate : The incidence rate is 3.9 with a 95% confidence interval from 3.7 to 4.1 and 362 average annual cases over 2018-2022.
• CI*Rank ⋔ : 11 (5, 22)
• Percent of Cases with Late Stage : 46.2

Washington¹

• Rate : The incidence rate is 3.9 with a 95% confidence interval from 3.7 to 4.1 and 381 average annual cases over 2018-2022.
• CI*Rank ⋔ : 10 (5, 20)
• Percent of Cases with Late Stage : 45.6

North Carolina²

• Rate : The incidence rate is 4.0 with a 95% confidence interval from 3.8 to 4.1 and 546 average annual cases over 2018-2022.
• CI*Rank ⋔ : 9 (5, 18)
• Percent of Cases with Late Stage : 44.4

Missouri²

• Rate : The incidence rate is 4.0 with a 95% confidence interval from 3.8 to 4.2 and 332 average annual cases over 2018-2022.
• CI*Rank ⋔ : 8 (3, 18)
• Percent of Cases with Late Stage : 46.7

Kentucky⁷

• Rate : The incidence rate is 4.1 with a 95% confidence interval from 3.9 to 4.4 and 246 average annual cases over 2018-2022.
• CI*Rank ⋔ : 7 (3, 16)
• Percent of Cases with Late Stage : 45.0

Alaska²

• Rate : The incidence rate is 4.2 with a 95% confidence interval from 3.6 to 5.0 and 34 average annual cases over 2018-2022.
• CI*Rank ⋔ : 6 (1, 32)
• Percent of Cases with Late Stage : 44.9

Georgia⁷

• Rate : The incidence rate is 4.3 with a 95% confidence interval from 4.1 to 4.5 and 547 average annual cases over 2018-2022.
• CI*Rank ⋔ : 5 (3, 8)
• Percent of Cases with Late Stage : 50.2

District of Columbia²

• Rate : The incidence rate is 4.4 with a 95% confidence interval from 3.7 to 5.1 and 31 average annual cases over 2018-2022.
• CI*Rank ⋔ : 4 (1, 31)
• Percent of Cases with Late Stage : 39.7

Rhode Island²

• Rate : The incidence rate is 4.4 with a 95% confidence interval from 3.9 to 4.9 and 65 average annual cases over 2018-2022.
• CI*Rank ⋔ : 3 (1, 20)
• Percent of Cases with Late Stage : 50.6

Louisiana⁷

• Rate : The incidence rate is 4.9 with a 95% confidence interval from 4.6 to 5.1 and 297 average annual cases over 2018-2022.
• CI*Rank ⋔ : 2 (1, 4)
• Percent of Cases with Late Stage : 46.0

Texas⁷

• Rate : The incidence rate is 5.0 with a 95% confidence interval from 4.9 to 5.1 and 1,621 average annual cases over 2018-2022.
• CI*Rank ⋔ : 1 (1, 3)
• Percent of Cases with Late Stage : 40.3

Notes:
Created by statecancerprofiles.cancer.gov on 03/09/2026 6:51 pm.

State Cancer Registries may provide more current or more local data.



† Incidence rates (cases per 100,000 population per year) are age-adjusted to the 2000 US standard population (SEER areas use 20 age groups and NPCR areas use 19 age groups). Rates are for invasive cancer only (except for bladder cancer which is invasive and in situ) or unless otherwise specified. Rates calculated using SEER*Stat. Population counts for denominators are based on Census populations as modified by NCI. The US Population Data File is used for SEER and NPCR incidence rates.

Rates are computed using cancers classified as malignant based on ICD-O-3. For more information see malignant.html.

^ Late Stage is defined as cases determined to be regional or distant. Due to changes in stage coding, Combined Summary Stage with Expanded Regional Codes (2004+) is used for data from Surveillance, Epidemiology, and End Results (SEER) databases and Merged Summary Stage is used for data from National Program of Cancer Registries databases. Due to the increased complexity with staging, other staging variables maybe used if necessary.

⋔ Results presented with the CI*Rank statistics help show the usefulness of ranks. For example, ranks for relatively rare diseases or less populated areas may be essentially meaningless because of their large variability, but ranks for more common diseases in densely populated regions can be very useful. The rates used in CI*Rank are all age-adjusted to the 2000 US standard population using 19 age groups for SEER and NPCR areas. More information about methodology can be found on the CI*Rank website.

¹ Source: National Program of Cancer Registries and Surveillance, Epidemiology, and End Results SEER*Stat Database - United States Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute. Based on the 2024 submission.

² Source: National Program of Cancer Registries SEER*Stat Database - United States Department of Health and Human Services, Centers for Disease Control and Prevention (based on the 2024 submission).

⁷ Source: SEER November 2024 submission.

Data for United States does not include Puerto Rico.