Interpretation of Incidence Rates Data
Incidence Rate Report by State
Colon & Rectum (All Stages^), 2021
All Races (includes Hispanic), Both Sexes, All Ages
Sorted by Rate
Explanation of Column HeadersObjective - The objective of *** is from the Healthy People 2020 project done by the Centers for Disease Control and Prevention.
Incidence Rate (95% Confidence Interval) - The incidence rate is based upon 100,000 people and is an annual rate (or average annual rate) based on the time period indicated. Rates are age-adjusted by 5-year age groups to the 2000 U.S. standard million population.Recent Trends - This is an interpretation of the AAPC/APC:
- Rising when 95% confidence interval of AAPC/APC is above 0.
- Stable when 95% confidence interval of AAPC/APC includes 0.
- Falling when 95% confidence interval of AAPC/APC is below 0.
AAPC/APC (95% Confidence Interval) - the change in rate over time
- Average Annual Percent Change - AAPCs are based upon APCs that were calculated by Joinpoint Regression Program
- Annual Percent Change - APCs calculated in SEER*Stat.
Other Notes
- Larger confidence intervals indicate less stability of the data. This is often due to low counts that are not quite low enough to be suppressed.
- Data is currently being suppressed if there are fewer than 16 counts for the time period.
Line by Line Interpretation of the Report
US (SEER+NPCR)1
- Rate : The incidence rate is 36.0 with a 95% confidence interval from 35.8 to 36.2 and 141,902 average annual cases over 2021.
- CI*Rank ⋔ : N/A
- Recent Trend : The trend is falling
because the trend is -1.1 with a 95% confidence interval from -1.3 to -0.9.
Mississippi2
- Rate : The incidence rate is 44.8 with a 95% confidence interval from 42.6 to 47.1 and 1,608 average annual cases over 2021.
- CI*Rank ⋔ : 1 (1, 7)
- Recent Trend : The trend is falling
because the trend is -1.0 with a 95% confidence interval from -1.2 to -0.7.
Kentucky7
- Rate : The incidence rate is 44.7 with a 95% confidence interval from 42.9 to 46.6 and 2,456 average annual cases over 2021.
- CI*Rank ⋔ : 2 (1, 7)
- Recent Trend : The trend is stable
because the trend is -1.1 with a 95% confidence interval from -1.7 to 0.3.
Louisiana7
- Rate : The incidence rate is 44.5 with a 95% confidence interval from 42.7 to 46.4 and 2,448 average annual cases over 2021.
- CI*Rank ⋔ : 3 (1, 6)
- Recent Trend : The trend is stable
because the trend is 0.1 with a 95% confidence interval from -1.1 to 1.8.
West Virginia2
- Rate : The incidence rate is 43.4 with a 95% confidence interval from 40.8 to 46.2 and 1,083 average annual cases over 2021.
- CI*Rank ⋔ : 4 (1, 11)
- Recent Trend : The trend is stable
because the trend is -0.7 with a 95% confidence interval from -1.4 to 0.7.
Oklahoma2
- Rate : The incidence rate is 42.6 with a 95% confidence interval from 40.7 to 44.6 and 1,971 average annual cases over 2021.
- CI*Rank ⋔ : 5 (1, 11)
- Recent Trend : The trend is stable
because the trend is -0.4 with a 95% confidence interval from -1.5 to 2.1.
Hawaii7
- Rate : The incidence rate is 40.8 with a 95% confidence interval from 37.9 to 44.0 and 766 average annual cases over 2021.
- CI*Rank ⋔ : 6 (1, 25)
- Recent Trend : The trend is stable
because the trend is 1.2 with a 95% confidence interval from -1.9 to 3.0.
North Dakota2
- Rate : The incidence rate is 40.6 with a 95% confidence interval from 36.3 to 45.3 and 352 average annual cases over 2021.
- CI*Rank ⋔ : 7 (1, 35)
- Recent Trend : The trend is falling
because the trend is -2.1 with a 95% confidence interval from -3.0 to -1.4.
Georgia7
- Rate : The incidence rate is 40.5 with a 95% confidence interval from 39.3 to 41.6 and 4,906 average annual cases over 2021.
- CI*Rank ⋔ : 8 (5, 15)
- Recent Trend : The trend is stable
because the trend is -0.5 with a 95% confidence interval from -2.1 to 0.7.
New Jersey7
- Rate : The incidence rate is 39.4 with a 95% confidence interval from 38.3 to 40.6 and 4,585 average annual cases over 2021.
- CI*Rank ⋔ : 9 (6, 20)
- Recent Trend : The trend is stable
because the trend is 0.5 with a 95% confidence interval from -1.3 to 1.6.
Missouri2
- Rate : The incidence rate is 39.4 with a 95% confidence interval from 37.9 to 40.9 and 3,012 average annual cases over 2021.
- CI*Rank ⋔ : 10 (6, 22)
- Recent Trend : The trend is stable
because the trend is -0.7 with a 95% confidence interval from -1.9 to 1.6.
Alabama2
- Rate : The incidence rate is 39.4 with a 95% confidence interval from 37.8 to 41.0 and 2,510 average annual cases over 2021.
- CI*Rank ⋔ : 11 (5, 23)
- Recent Trend : The trend is falling
because the trend is -1.8 with a 95% confidence interval from -2.9 to -1.3.
Alaska2
- Rate : The incidence rate is 39.4 with a 95% confidence interval from 34.8 to 44.4 and 292 average annual cases over 2021.
- CI*Rank ⋔ : 12 (1, 43)
- Recent Trend : The trend is falling
because the trend is -1.8 with a 95% confidence interval from -2.3 to -1.2.
Iowa7
- Rate : The incidence rate is 39.1 with a 95% confidence interval from 37.1 to 41.2 and 1,559 average annual cases over 2021.
- CI*Rank ⋔ : 13 (5, 26)
- Recent Trend : The trend is stable
because the trend is -1.5 with a 95% confidence interval from -2.2 to 0.2.
Ohio2
- Rate : The incidence rate is 38.3 with a 95% confidence interval from 37.3 to 39.4 and 5,664 average annual cases over 2021.
- CI*Rank ⋔ : 14 (8, 24)
- Recent Trend : The trend is falling
because the trend is -1.9 with a 95% confidence interval from -3.2 to -1.3.
Illinois7
- Rate : The incidence rate is 38.2 with a 95% confidence interval from 37.2 to 39.2 and 5,878 average annual cases over 2021.
- CI*Rank ⋔ : 15 (9, 24)
- Recent Trend : The trend is falling
because the trend is -1.8 with a 95% confidence interval from -2.3 to -0.5.
South Dakota2
- Rate : The incidence rate is 38.1 with a 95% confidence interval from 34.3 to 42.1 and 408 average annual cases over 2021.
- CI*Rank ⋔ : 16 (3, 42)
- Recent Trend : The trend is stable
because the trend is -1.7 with a 95% confidence interval from -2.4 to 0.3.
Arkansas2
- Rate : The incidence rate is 38.0 with a 95% confidence interval from 36.0 to 40.1 and 1,417 average annual cases over 2021.
- CI*Rank ⋔ : 17 (7, 31)
- Recent Trend : The trend is stable
because the trend is -0.2 with a 95% confidence interval from -1.2 to 2.6.
Idaho7
- Rate : The incidence rate is 37.9 with a 95% confidence interval from 35.3 to 40.7 and 837 average annual cases over 2021.
- CI*Rank ⋔ : 18 (5, 35)
- Recent Trend : The trend is stable
because the trend is 1.7 with a 95% confidence interval from -0.5 to 3.8.
Texas7
- Rate : The incidence rate is 37.9 with a 95% confidence interval from 37.2 to 38.6 and 11,563 average annual cases over 2021.
- CI*Rank ⋔ : 19 (11, 24)
- Recent Trend : The trend is stable
because the trend is -0.1 with a 95% confidence interval from -0.5 to 0.2.
Montana2
- Rate : The incidence rate is 37.7 with a 95% confidence interval from 34.4 to 41.2 and 543 average annual cases over 2021.
- CI*Rank ⋔ : 20 (4, 41)
- Recent Trend : The trend is falling
because the trend is -1.9 with a 95% confidence interval from -2.5 to -1.3.
Nebraska2
- Rate : The incidence rate is 37.4 with a 95% confidence interval from 34.9 to 40.1 and 855 average annual cases over 2021.
- CI*Rank ⋔ : 21 (6, 38)
- Recent Trend : The trend is falling
because the trend is -3.6 with a 95% confidence interval from -5.5 to -2.5.
Puerto Rico2
- Rate : The incidence rate is 37.2 with a 95% confidence interval from 35.4 to 39.1 and 1,786 average annual cases over 2021.
- CI*Rank ⋔ : N/A
- Recent Trend : The trend is falling
because the trend is -3.1 with a 95% confidence interval from -4.6 to -1.3.
Tennessee2
- Rate : The incidence rate is 37.1 with a 95% confidence interval from 35.8 to 38.5 and 3,154 average annual cases over 2021.
- CI*Rank ⋔ : 22 (11, 31)
- Recent Trend : The trend is stable
because the trend is -0.8 with a 95% confidence interval from -1.5 to 0.6.
Kansas2
- Rate : The incidence rate is 37.0 with a 95% confidence interval from 34.9 to 39.1 and 1,293 average annual cases over 2021.
- CI*Rank ⋔ : 23 (8, 36)
- Recent Trend : The trend is stable
because the trend is -0.5 with a 95% confidence interval from -1.9 to 2.1.
Minnesota2
- Rate : The incidence rate is 36.9 with a 95% confidence interval from 35.4 to 38.4 and 2,512 average annual cases over 2021.
- CI*Rank ⋔ : 24 (12, 32)
- Recent Trend : The trend is stable
because the trend is -0.7 with a 95% confidence interval from -1.5 to 1.1.
New York7
- Rate : The incidence rate is 36.4 with a 95% confidence interval from 35.6 to 37.1 and 8,997 average annual cases over 2021.
- CI*Rank ⋔ : 25 (18, 31)
- Recent Trend : The trend is falling
because the trend is -1.1 with a 95% confidence interval from -1.5 to -0.5.
Florida2
- Rate : The incidence rate is 35.8 with a 95% confidence interval from 35.1 to 36.5 and 11,073 average annual cases over 2021.
- CI*Rank ⋔ : 26 (21, 33)
- Recent Trend : The trend is falling
because the trend is -1.1 with a 95% confidence interval from -1.5 to -0.6.
Maine2
- Rate : The incidence rate is 35.4 with a 95% confidence interval from 32.7 to 38.3 and 706 average annual cases over 2021.
- CI*Rank ⋔ : 27 (10, 45)
- Recent Trend : The trend is stable
because the trend is -0.8 with a 95% confidence interval from -2.1 to 2.0.
Pennsylvania2
- Rate : The incidence rate is 35.4 with a 95% confidence interval from 34.4 to 36.3 and 6,042 average annual cases over 2021.
- CI*Rank ⋔ : 28 (21, 37)
- Recent Trend : The trend is falling
because the trend is -1.9 with a 95% confidence interval from -2.5 to -0.5.
District of Columbia2
- Rate : The incidence rate is 35.2 with a 95% confidence interval from 30.7 to 40.1 and 231 average annual cases over 2021.
- CI*Rank ⋔ : 29 (5, 50)
- Recent Trend : The trend is falling
because the trend is -2.6 with a 95% confidence interval from -3.4 to -1.9.
North Carolina2
- Rate : The incidence rate is 35.0 with a 95% confidence interval from 34.0 to 36.1 and 4,496 average annual cases over 2021.
- CI*Rank ⋔ : 30 (22, 39)
- Recent Trend : The trend is falling
because the trend is -1.6 with a 95% confidence interval from -2.8 to -0.9.
Connecticut7
- Rate : The incidence rate is 35.0 with a 95% confidence interval from 33.2 to 36.8 and 1,578 average annual cases over 2021.
- CI*Rank ⋔ : 31 (18, 43)
- Recent Trend : The trend is stable
because the trend is -0.8 with a 95% confidence interval from -2.1 to 1.4.
Wisconsin2
- Rate : The incidence rate is 34.6 with a 95% confidence interval from 33.2 to 36.0 and 2,549 average annual cases over 2021.
- CI*Rank ⋔ : 32 (22, 43)
- Recent Trend : The trend is stable
because the trend is -1.1 with a 95% confidence interval from -1.8 to 0.3.
Washington4
- Rate : The incidence rate is 34.6 with a 95% confidence interval from 33.3 to 35.8 and 3,093 average annual cases over 2021.
- CI*Rank ⋔ : 33 (23, 42)
- Recent Trend : The trend is stable
because the trend is -0.7 with a 95% confidence interval from -1.3 to 0.3.
Wyoming2
- Rate : The incidence rate is 34.5 with a 95% confidence interval from 30.2 to 39.2 and 251 average annual cases over 2021.
- CI*Rank ⋔ : 34 (6, 50)
- Recent Trend : The trend is stable
because the trend is 1.9 with a 95% confidence interval from -2.1 to 7.3.
Maryland2
- Rate : The incidence rate is 34.3 with a 95% confidence interval from 32.9 to 35.7 and 2,542 average annual cases over 2021.
- CI*Rank ⋔ : 35 (23, 43)
- Recent Trend : The trend is stable
because the trend is -0.6 with a 95% confidence interval from -1.5 to 1.2.
South Carolina2
- Rate : The incidence rate is 34.2 with a 95% confidence interval from 32.8 to 35.7 and 2,275 average annual cases over 2021.
- CI*Rank ⋔ : 36 (23, 44)
- Recent Trend : The trend is stable
because the trend is -1.4 with a 95% confidence interval from -2.3 to 1.3.
California7
- Rate : The incidence rate is 33.6 with a 95% confidence interval from 33.1 to 34.2 and 15,096 average annual cases over 2021.
- CI*Rank ⋔ : 37 (31, 43)
- Recent Trend : The trend is falling
because the trend is -1.0 with a 95% confidence interval from -1.4 to -0.5.
Virginia2
- Rate : The incidence rate is 33.4 with a 95% confidence interval from 32.3 to 34.6 and 3,441 average annual cases over 2021.
- CI*Rank ⋔ : 38 (28, 45)
- Recent Trend : The trend is falling
because the trend is -1.1 with a 95% confidence interval from -1.5 to -0.5.
Michigan2
- Rate : The incidence rate is 33.2 with a 95% confidence interval from 32.2 to 34.3 and 4,221 average annual cases over 2021.
- CI*Rank ⋔ : 39 (30, 45)
- Recent Trend : The trend is falling
because the trend is -3.3 with a 95% confidence interval from -5.9 to -1.3.
Vermont2
- Rate : The incidence rate is 33.0 with a 95% confidence interval from 29.0 to 37.4 and 278 average annual cases over 2021.
- CI*Rank ⋔ : 40 (12, 50)
- Recent Trend : The trend is stable
because the trend is -0.6 with a 95% confidence interval from -2.9 to 3.0.
Nevada2
- Rate : The incidence rate is 32.9 with a 95% confidence interval from 31.1 to 34.9 and 1,236 average annual cases over 2021.
- CI*Rank ⋔ : 41 (26, 48)
- Recent Trend : The trend is falling
because the trend is -2.5 with a 95% confidence interval from -2.8 to -2.2.
New Mexico7
- Rate : The incidence rate is 32.7 with a 95% confidence interval from 30.5 to 35.1 and 863 average annual cases over 2021.
- CI*Rank ⋔ : 42 (23, 49)
- Recent Trend : The trend is stable
because the trend is -0.3 with a 95% confidence interval from -1.4 to 2.0.
New Hampshire2
- Rate : The incidence rate is 32.3 with a 95% confidence interval from 29.6 to 35.1 and 601 average annual cases over 2021.
- CI*Rank ⋔ : 43 (23, 50)
- Recent Trend : The trend is stable
because the trend is -1.3 with a 95% confidence interval from -2.5 to 2.0.
Colorado2
- Rate : The incidence rate is 31.7 with a 95% confidence interval from 30.3 to 33.1 and 2,047 average annual cases over 2021.
- CI*Rank ⋔ : 44 (35, 49)
- Recent Trend : The trend is falling
because the trend is -1.1 with a 95% confidence interval from -1.5 to -0.7.
Delaware2
- Rate : The incidence rate is 31.7 with a 95% confidence interval from 28.5 to 35.0 and 422 average annual cases over 2021.
- CI*Rank ⋔ : 45 (23, 50)
- Recent Trend : The trend is falling
because the trend is -5.0 with a 95% confidence interval from -6.6 to -3.8.
Rhode Island2
- Rate : The incidence rate is 31.1 with a 95% confidence interval from 28.2 to 34.3 and 442 average annual cases over 2021.
- CI*Rank ⋔ : 46 (26, 50)
- Recent Trend : The trend is stable
because the trend is 0.2 with a 95% confidence interval from -3.5 to 3.6.
Oregon2
- Rate : The incidence rate is 30.8 with a 95% confidence interval from 29.2 to 32.3 and 1,628 average annual cases over 2021.
- CI*Rank ⋔ : 47 (39, 50)
- Recent Trend : The trend is stable
because the trend is -1.6 with a 95% confidence interval from -2.3 to 0.0.
Massachusetts7
- Rate : The incidence rate is 30.1 with a 95% confidence interval from 28.9 to 31.3 and 2,590 average annual cases over 2021.
- CI*Rank ⋔ : 48 (42, 50)
- Recent Trend : The trend is falling
because the trend is -2.5 with a 95% confidence interval from -3.0 to -1.7.
Utah7
- Rate : The incidence rate is 29.5 with a 95% confidence interval from 27.6 to 31.6 and 882 average annual cases over 2021.
- CI*Rank ⋔ : 49 (41, 50)
- Recent Trend : The trend is stable
because the trend is 0.5 with a 95% confidence interval from -2.1 to 3.5.
Arizona2
- Rate : The incidence rate is 29.3 with a 95% confidence interval from 28.2 to 30.5 and 2,666 average annual cases over 2021.
- CI*Rank ⋔ : 50 (44, 50)
- Recent Trend : The trend is falling
because the trend is -1.9 with a 95% confidence interval from -2.3 to -1.6.
- Rate : Data not available for this combination of data selections.
- CI*Rank ⋔ : N/A
- Recent Trend : Data not available for this combination of data selections.
Notes:
Created by statecancerprofiles.cancer.gov on 07/14/2025 6:54 pm.
State Cancer Registries may provide more current or more local data.
Trend
Rising when 95% confidence interval of average annual percent change is above 0.
Stable when 95% confidence interval of average annual percent change includes 0.
Falling when 95% confidence interval of average annual percent change is below 0.
Rising when 95% confidence interval of average annual percent change is above 0.
Stable when 95% confidence interval of average annual percent change includes 0.
Falling when 95% confidence interval of average annual percent change is below 0.
† Incidence rates (cases per 100,000 population per year) are age-adjusted to the 2000 US standard population (19 age groups: <1, 1-4, 5-9, ... , 80-84, 85+). Rates are for invasive cancer only (except for bladder cancer which is invasive and in situ) or unless otherwise specified. Rates calculated using SEER*Stat. Population counts for denominators are based on Census populations as modified by NCI. The US Population Data File is used for SEER and NPCR incidence rates.
‡ Incidence data come from different sources. The Average Annual Percent Change (AAPC) is based on the APCs calculated by Joinpoint. Due to data availability issues, the time period used in the calculation of the joinpoint regression model may differ for selected counties.
Rates and trends are computed using different standards for malignancy. For more information see malignant.html.
^ All Stages refers to any stage in the Surveillance, Epidemiology, and End Results (SEER) Summary/Historic Combined Summary Stage (2004+).
⋔ Results presented with the CI*Rank statistics help show the usefulness of ranks. For example, ranks for relatively rare diseases or less populated areas may be essentially meaningless because of their large variability, but ranks for more common diseases in densely populated regions can be very useful. More information about methodology can be found on the CI*Rank website.
Data not available for this combination of data selections.
1 Source: National Program of Cancer Registries and Surveillance, Epidemiology, and End Results SEER*Stat Database - United States Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute. Based on the 2023 submission.
2 Source: National Program of Cancer Registries SEER*Stat Database - United States Department of Health and Human Services, Centers for Disease Control and Prevention (based on the 2023 submission).
4 Source: National Program of Cancer Registries and Surveillance, Epidemiology, and End Results SEER*Stat Database - United States Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute. Based on the 2023 submission.
7 Source: SEER November 2023 submission.
8 Source: Incidence data provided by the SEER Program. AAPCs are calculated by the Joinpoint Regression Program and are based on APCs. Data are age-adjusted to the 2000 US standard population (19 age groups: <1, 1-4, 5-9, ... , 80-84,85+). Rates are for invasive cancer only (except for bladder cancer which is invasive and in situ) or unless otherwise specified. Population counts for denominators are based on Census populations as modified by NCI. The US Population Data File is used with SEER November 2023 data.
Data for the United States does not include data from Indiana.
Data for the United States does not include Puerto Rico.