State Cancer Profiles

Interpretation of Incidence Rates Data

Incidence Rate Report by State

Liver & Bile Duct (All Stages^), 2018-2022

All Races (includes Hispanic), Both Sexes, All Ages

Sorted by Count

Explanation of Column Headers
Incidence Rate (95% Confidence Interval) - The incidence rate is based upon 100,000 people and is an annual rate (or average annual rate) based on the time period indicated. Rates are age-adjusted by 5-year age groups to the 2000 U.S. standard million population.

Recent Trends - This is an interpretation of the AAPC/APC:

• Rising when 95% confidence interval of AAPC/APC is above 0.
• Stable when 95% confidence interval of AAPC/APC includes 0.
• Falling when 95% confidence interval of AAPC/APC is below 0.

AAPC/APC (95% Confidence Interval) - the change in rate over time

• Average Annual Percent Change - AAPCs are based upon APCs that were calculated by Joinpoint Regression Program
• Annual Percent Change - APCs calculated in SEER*Stat.

Other Notes

• Larger confidence intervals indicate less stability of the data. This is often due to low counts that are not quite low enough to be suppressed.
• Data is currently being suppressed if there are fewer than 16 counts for the time period.

Line by Line Interpretation of the Report

US (SEER+NPCR)¹

• Rate : The incidence rate is 8.6 with a 95% confidence interval from 8.6 to 8.7 and 37,201 average annual cases over 2018-2022.
• CI*Rank ⋔ : N/A
• Recent Trend : The trend is falling because the trend is -1.7 with a 95% confidence interval from -2.2 to -1.2.

California⁷

• Rate : The incidence rate is 9.6 with a 95% confidence interval from 9.4 to 9.7 and 4,510 average annual cases over 2018-2022.
• CI*Rank ⋔ : 5 (4, 8)
• Recent Trend : The trend is falling because the trend is -3.1 with a 95% confidence interval from -4.3 to -1.7.

Texas⁷

• Rate : The incidence rate is 12.6 with a 95% confidence interval from 12.4 to 12.8 and 4,022 average annual cases over 2018-2022.
• CI*Rank ⋔ : 1 (1, 2)
• Recent Trend : The trend is stable because the trend is 0.5 with a 95% confidence interval from -0.4 to 1.3.

Florida²

• Rate : The incidence rate is 8.3 with a 95% confidence interval from 8.2 to 8.5 and 2,741 average annual cases over 2018-2022.
• CI*Rank ⋔ : 22 (16, 29)
• Recent Trend : The trend is stable because the trend is -1.2 with a 95% confidence interval from -2.5 to 0.3.

New York⁷

• Rate : The incidence rate is 8.1 with a 95% confidence interval from 8.0 to 8.3 and 2,146 average annual cases over 2018-2022.
• CI*Rank ⋔ : 28 (21, 33)
• Recent Trend : The trend is falling because the trend is -2.6 with a 95% confidence interval from -3.8 to -1.8.

Pennsylvania²

• Rate : The incidence rate is 8.3 with a 95% confidence interval from 8.1 to 8.5 and 1,542 average annual cases over 2018-2022.
• CI*Rank ⋔ : 24 (16, 31)
• Recent Trend : The trend is falling because the trend is -1.3 with a 95% confidence interval from -2.9 to -0.2.

Illinois⁷

• Rate : The incidence rate is 8.2 with a 95% confidence interval from 8.0 to 8.4 and 1,332 average annual cases over 2018-2022.
• CI*Rank ⋔ : 26 (18, 33)
• Recent Trend : The trend is falling because the trend is -2.7 with a 95% confidence interval from -4.6 to -0.6.

Ohio²

• Rate : The incidence rate is 7.6 with a 95% confidence interval from 7.4 to 7.8 and 1,236 average annual cases over 2018-2022.
• CI*Rank ⋔ : 34 (31, 40)
• Recent Trend : The trend is falling because the trend is -2.7 with a 95% confidence interval from -4.3 to -1.5.

North Carolina²

• Rate : The incidence rate is 9.0 with a 95% confidence interval from 8.7 to 9.2 and 1,231 average annual cases over 2018-2022.
• CI*Rank ⋔ : 10 (6, 17)
• Recent Trend : The trend is stable because the trend is 0.0 with a 95% confidence interval from -1.8 to 1.3.

Georgia⁷

• Rate : The incidence rate is 8.6 with a 95% confidence interval from 8.3 to 8.8 and 1,089 average annual cases over 2018-2022.
• CI*Rank ⋔ : 17 (10, 26)
• Recent Trend : The trend is stable because the trend is -0.2 with a 95% confidence interval from -2.0 to 1.0.

Michigan²

• Rate : The incidence rate is 7.2 with a 95% confidence interval from 7.0 to 7.4 and 1,004 average annual cases over 2018-2022.
• CI*Rank ⋔ : 40 (35, 47)
• Recent Trend : The trend is falling because the trend is -1.4 with a 95% confidence interval from -3.4 to -0.1.

New Jersey⁷

• Rate : The incidence rate is 8.0 with a 95% confidence interval from 7.8 to 8.2 and 969 average annual cases over 2018-2022.
• CI*Rank ⋔ : 32 (22, 35)
• Recent Trend : The trend is stable because the trend is -1.7 with a 95% confidence interval from -3.1 to 0.1.

Washington¹

• Rate : The incidence rate is 8.6 with a 95% confidence interval from 8.4 to 8.9 and 836 average annual cases over 2018-2022.
• CI*Rank ⋔ : 14 (8, 25)
• Recent Trend : The trend is falling because the trend is -4.2 with a 95% confidence interval from -6.3 to -1.9.

Virginia²

• Rate : The incidence rate is 7.5 with a 95% confidence interval from 7.2 to 7.7 and 828 average annual cases over 2018-2022.
• CI*Rank ⋔ : 36 (32, 44)
• Recent Trend : The trend is stable because the trend is -0.2 with a 95% confidence interval from -5.3 to 2.3.

Massachusetts²

• Rate : The incidence rate is 8.4 with a 95% confidence interval from 8.1 to 8.7 and 785 average annual cases over 2018-2022.
• CI*Rank ⋔ : 21 (11, 31)
• Recent Trend : The trend is falling because the trend is -4.9 with a 95% confidence interval from -8.3 to -2.2.

Tennessee²

• Rate : The incidence rate is 8.6 with a 95% confidence interval from 8.3 to 8.8 and 784 average annual cases over 2018-2022.
• CI*Rank ⋔ : 18 (9, 27)
• Recent Trend : The trend is stable because the trend is -1.3 with a 95% confidence interval from -3.6 to 0.1.

Arizona²

• Rate : The incidence rate is 7.9 with a 95% confidence interval from 7.6 to 8.2 and 773 average annual cases over 2018-2022.
• CI*Rank ⋔ : 33 (23, 37)
• Recent Trend : The trend is falling because the trend is -2.3 with a 95% confidence interval from -5.0 to -0.4.

Missouri²

• Rate : The incidence rate is 8.5 with a 95% confidence interval from 8.2 to 8.8 and 712 average annual cases over 2018-2022.
• CI*Rank ⋔ : 19 (10, 29)
• Recent Trend : The trend is rising because the trend is 1.5 with a 95% confidence interval from 0.1 to 2.3.

Indiana²

• Rate : The incidence rate is 8.2 with a 95% confidence interval from 7.9 to 8.5 and 710 average annual cases over 2018-2022.
• CI*Rank ⋔ : 27 (16, 34)
• Recent Trend : The trend is falling because the trend is -4.5 with a 95% confidence interval from -6.2 to -2.1.

Maryland²

• Rate : The incidence rate is 8.4 with a 95% confidence interval from 8.2 to 8.7 and 669 average annual cases over 2018-2022.
• CI*Rank ⋔ : 20 (11, 31)
• Recent Trend : The trend is falling because the trend is -2.6 with a 95% confidence interval from -5.5 to -0.5.

Louisiana⁷

• Rate : The incidence rate is 10.7 with a 95% confidence interval from 10.3 to 11.0 and 646 average annual cases over 2018-2022.
• CI*Rank ⋔ : 3 (2, 4)
• Recent Trend : The trend is stable because the trend is -3.1 with a 95% confidence interval from -8.5 to 2.7.

Wisconsin²

• Rate : The incidence rate is 7.4 with a 95% confidence interval from 7.2 to 7.7 and 601 average annual cases over 2018-2022.
• CI*Rank ⋔ : 37 (32, 45)
• Recent Trend : The trend is stable because the trend is -0.8 with a 95% confidence interval from -3.3 to 0.8.

Alabama²

• Rate : The incidence rate is 8.6 with a 95% confidence interval from 8.3 to 8.9 and 589 average annual cases over 2018-2022.
• CI*Rank ⋔ : 16 (9, 28)
• Recent Trend : The trend is stable because the trend is 1.5 with a 95% confidence interval from -2.1 to 3.5.

Minnesota²

• Rate : The incidence rate is 8.0 with a 95% confidence interval from 7.7 to 8.3 and 581 average annual cases over 2018-2022.
• CI*Rank ⋔ : 30 (18, 36)
• Recent Trend : The trend is stable because the trend is -0.6 with a 95% confidence interval from -5.3 to 2.8.

South Carolina²

• Rate : The incidence rate is 8.0 with a 95% confidence interval from 7.7 to 8.3 and 578 average annual cases over 2018-2022.
• CI*Rank ⋔ : 31 (19, 36)
• Recent Trend : The trend is stable because the trend is -1.3 with a 95% confidence interval from -6.7 to 1.6.

Kentucky⁷

• Rate : The incidence rate is 9.2 with a 95% confidence interval from 8.8 to 9.5 and 546 average annual cases over 2018-2022.
• CI*Rank ⋔ : 8 (4, 15)
• Recent Trend : The trend is stable because the trend is 1.1 with a 95% confidence interval from -1.1 to 2.5.

Oregon²

• Rate : The incidence rate is 8.8 with a 95% confidence interval from 8.5 to 9.2 and 516 average annual cases over 2018-2022.
• CI*Rank ⋔ : 12 (6, 24)
• Recent Trend : The trend is falling because the trend is -5.4 with a 95% confidence interval from -8.4 to -2.7.

Colorado²

• Rate : The incidence rate is 7.1 with a 95% confidence interval from 6.8 to 7.4 and 494 average annual cases over 2018-2022.
• CI*Rank ⋔ : 43 (35, 48)
• Recent Trend : The trend is falling because the trend is -1.7 with a 95% confidence interval from -4.4 to -0.1.

Oklahoma²

• Rate : The incidence rate is 9.3 with a 95% confidence interval from 9.0 to 9.7 and 469 average annual cases over 2018-2022.
• CI*Rank ⋔ : 7 (4, 14)
• Recent Trend : The trend is stable because the trend is 1.5 with a 95% confidence interval from -4.7 to 3.9.

Puerto Rico²

• Rate : The incidence rate is 7.8 with a 95% confidence interval from 7.5 to 8.2 and 405 average annual cases over 2018-2022.
• CI*Rank ⋔ : N/A
• Recent Trend : The trend is falling because the trend is -3.0 with a 95% confidence interval from -6.6 to -0.1.

Connecticut⁷

• Rate : The incidence rate is 8.1 with a 95% confidence interval from 7.7 to 8.4 and 405 average annual cases over 2018-2022.
• CI*Rank ⋔ : 29 (15, 36)
• Recent Trend : The trend is stable because the trend is 0.3 with a 95% confidence interval from -1.4 to 1.5.

Arkansas²

• Rate : The incidence rate is 8.9 with a 95% confidence interval from 8.5 to 9.4 and 357 average annual cases over 2018-2022.
• CI*Rank ⋔ : 11 (5, 24)
• Recent Trend : The trend is stable because the trend is 0.2 with a 95% confidence interval from -6.8 to 4.0.

Mississippi²

• Rate : The incidence rate is 8.7 with a 95% confidence interval from 8.3 to 9.1 and 339 average annual cases over 2018-2022.
• CI*Rank ⋔ : 13 (7, 28)
• Recent Trend : The trend is stable because the trend is -2.1 with a 95% confidence interval from -6.2 to 1.4.

Iowa⁷

• Rate : The incidence rate is 7.4 with a 95% confidence interval from 7.0 to 7.8 and 314 average annual cases over 2018-2022.
• CI*Rank ⋔ : 39 (31, 46)
• Recent Trend : The trend is stable because the trend is 0.3 with a 95% confidence interval from -3.1 to 3.6.

Nevada²

• Rate : The incidence rate is 7.4 with a 95% confidence interval from 7.0 to 7.8 and 293 average annual cases over 2018-2022.
• CI*Rank ⋔ : 38 (30, 47)
• Recent Trend : The trend is rising because the trend is 1.2 with a 95% confidence interval from 0.3 to 2.2.

New Mexico⁷

• Rate : The incidence rate is 9.8 with a 95% confidence interval from 9.3 to 10.3 and 285 average annual cases over 2018-2022.
• CI*Rank ⋔ : 4 (3, 11)
• Recent Trend : The trend is falling because the trend is -3.2 with a 95% confidence interval from -7.7 to -0.2.

Kansas²

• Rate : The incidence rate is 7.2 with a 95% confidence interval from 6.8 to 7.6 and 269 average annual cases over 2018-2022.
• CI*Rank ⋔ : 42 (33, 48)
• Recent Trend : The trend is stable because the trend is -1.0 with a 95% confidence interval from -4.9 to 1.6.

West Virginia²

• Rate : The incidence rate is 8.3 with a 95% confidence interval from 7.8 to 8.8 and 225 average annual cases over 2018-2022.
• CI*Rank ⋔ : 23 (9, 35)
• Recent Trend : The trend is stable because the trend is 0.4 with a 95% confidence interval from -4.0 to 3.9.

Utah⁷

• Rate : The incidence rate is 7.0 with a 95% confidence interval from 6.6 to 7.5 and 214 average annual cases over 2018-2022.
• CI*Rank ⋔ : 45 (34, 48)
• Recent Trend : The trend is stable because the trend is 1.9 with a 95% confidence interval from -0.3 to 3.2.

Hawaii⁷

• Rate : The incidence rate is 9.2 with a 95% confidence interval from 8.6 to 9.8 and 187 average annual cases over 2018-2022.
• CI*Rank ⋔ : 9 (4, 25)
• Recent Trend : The trend is falling because the trend is -3.3 with a 95% confidence interval from -5.8 to -1.7.

Idaho⁷

• Rate : The incidence rate is 7.5 with a 95% confidence interval from 7.0 to 8.1 and 176 average annual cases over 2018-2022.
• CI*Rank ⋔ : 35 (23, 47)
• Recent Trend : The trend is stable because the trend is -1.3 with a 95% confidence interval from -5.4 to 1.1.

Maine²

• Rate : The incidence rate is 7.1 with a 95% confidence interval from 6.6 to 7.6 and 152 average annual cases over 2018-2022.
• CI*Rank ⋔ : 44 (31, 49)
• Recent Trend : The trend is rising because the trend is 3.0 with a 95% confidence interval from 2.0 to 4.2.

Nebraska²

• Rate : The incidence rate is 6.1 with a 95% confidence interval from 5.7 to 6.6 and 148 average annual cases over 2018-2022.
• CI*Rank ⋔ : 49 (45, 50)
• Recent Trend : The trend is stable because the trend is 0.8 with a 95% confidence interval from -2.8 to 2.0.

New Hampshire²

• Rate : The incidence rate is 6.6 with a 95% confidence interval from 6.1 to 7.2 and 136 average annual cases over 2018-2022.
• CI*Rank ⋔ : 47 (38, 50)
• Recent Trend : The trend is stable because the trend is -1.7 with a 95% confidence interval from -11.0 to 3.2.

Rhode Island²

• Rate : The incidence rate is 8.6 with a 95% confidence interval from 7.9 to 9.3 and 129 average annual cases over 2018-2022.
• CI*Rank ⋔ : 15 (4, 35)
• Recent Trend : The trend is stable because the trend is -6.0 with a 95% confidence interval from -12.7 to 1.1.

Delaware²

• Rate : The incidence rate is 8.2 with a 95% confidence interval from 7.6 to 8.9 and 121 average annual cases over 2018-2022.
• CI*Rank ⋔ : 25 (7, 41)
• Recent Trend : The trend is stable because the trend is -0.5 with a 95% confidence interval from -3.0 to 1.2.

Montana²

• Rate : The incidence rate is 7.2 with a 95% confidence interval from 6.6 to 7.8 and 116 average annual cases over 2018-2022.
• CI*Rank ⋔ : 41 (26, 49)
• Recent Trend : The trend is rising because the trend is 4.1 with a 95% confidence interval from 3.0 to 5.5.

South Dakota²

• Rate : The incidence rate is 6.8 with a 95% confidence interval from 6.1 to 7.5 and 80 average annual cases over 2018-2022.
• CI*Rank ⋔ : 46 (32, 50)
• Recent Trend : The trend is stable because the trend is -1.7 with a 95% confidence interval from -11.2 to 3.2.

District of Columbia²

• Rate : The incidence rate is 11.1 with a 95% confidence interval from 10.1 to 12.3 and 79 average annual cases over 2018-2022.
• CI*Rank ⋔ : 2 (1, 5)
• Recent Trend : The trend is falling because the trend is -2.9 with a 95% confidence interval from -5.4 to -1.0.

Alaska²

• Rate : The incidence rate is 9.5 with a 95% confidence interval from 8.5 to 10.5 and 76 average annual cases over 2018-2022.
• CI*Rank ⋔ : 6 (2, 29)
• Recent Trend : The trend is rising because the trend is 1.7 with a 95% confidence interval from 0.5 to 3.3.

North Dakota²

• Rate : The incidence rate is 6.5 with a 95% confidence interval from 5.8 to 7.3 and 61 average annual cases over 2018-2022.
• CI*Rank ⋔ : 48 (34, 50)
• Recent Trend : The trend is rising because the trend is 4.1 with a 95% confidence interval from 2.2 to 6.6.

Vermont²

• Rate : The incidence rate is 5.9 with a 95% confidence interval from 5.2 to 6.7 and 59 average annual cases over 2018-2022.
• CI*Rank ⋔ : 50 (44, 51)
• Recent Trend : The trend is stable because the trend is -1.1 with a 95% confidence interval from -5.5 to 1.1.

Wyoming²

• Rate : The incidence rate is 4.8 with a 95% confidence interval from 4.1 to 5.6 and 40 average annual cases over 2018-2022.
• CI*Rank ⋔ : 51 (50, 51)
• Recent Trend : The trend is stable because the trend is -5.0 with a 95% confidence interval from -15.5 to 0.6.

Notes:
Created by statecancerprofiles.cancer.gov on 02/18/2026 7:56 pm.

State Cancer Registries may provide more current or more local data.

† Incidence rates (cases per 100,000 population per year) are age-adjusted to the 2000 US standard population (SEER areas use 20 age groups and NPCR areas use 19 age groups). Rates are for invasive cancer only (except for bladder cancer which is invasive and in situ) or unless otherwise specified. Rates calculated using SEER*Stat. Population counts for denominators are based on Census populations as modified by NCI. The US Population Data File is used for SEER and NPCR incidence rates.

Rates and trends are computed using different standards for malignancy. For more information see malignant.html.

^ All Stages refers to any stage. Due to changes in stage coding, Combined Summary Stage with Expanded Regional Codes (2004+) is used for data from Surveillance, Epidemiology, and End Results (SEER) databases and Merged Summary Stage is used for data from National Program of Cancer Registries databases. Due to the increased complexity with staging, other staging variables maybe used if necessary.

Source: SEER and NPCR data. For more specific information please see the table.

Data for United States does not include Puerto Rico.